NOAEL Data Cosmetic Ingredient

Cyclododecane, 1-methoxy-1-methyl-

Also known as: BRN 2238172, EINECS 253-534-3, 1-Methylcyclododecyl methyl ether, 1-Methyl-1-methoxycyclododecane

CAS 37514-30-0

Cyclododecane, 1-methoxy-1-methyl- (CAS 37514-30-0) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Madrox →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 10 fields
Name
Cyclododecane, 1-methoxy-1-methyl-
CAS Number
37514-30-0
DTXSID
DTXSID4068034
Molecular Formula
C14H28O
InChI Key
QACBYNLZEUNZSC-UHFFFAOYSA-N
Monoisotopic Mass
212.214016
Synonyms
BRN 2238172EINECS 253-534-31-Methylcyclododecyl methyl ether1-Methyl-1-methoxycyclododecane

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Fragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
IFRA TransparencyIFRAIFRA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
FJ62QR3MEQUNIIFDA UNII substance identifier--openFDA substances
FJ62QR3MEQUNIIFDA UNII substance identifier--openFDA substances
FJ62QR3MEQUNIIFDA UNII substance identifier--openFDA substances
FJ62QR3MEQUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
13500ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 7 of 7 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Cyclododecane, 1-methoxy-1-methyl-?

Cyclododecane, 1-methoxy-1-methyl- has 7 NOAEL studies in the database. The lowest reported value is FJ62QR3MEQ UNII. Source: openFDA substances.

What regulatory lists include Cyclododecane, 1-methoxy-1-methyl-?

Cyclododecane, 1-methoxy-1-methyl- appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.

Is Cyclododecane, 1-methoxy-1-methyl- used in cosmetics?

Yes, Cyclododecane, 1-methoxy-1-methyl- is also indexed as a cosmetic ingredient under the name Madrox. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Cyclododecane, 1-methoxy-1-methyl- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Cyclododecane, 1-methoxy-1-methyl- have different safety status in cosmetics vs industrial chemicals?

Cyclododecane, 1-methoxy-1-methyl- is prohibited in EU cosmetics but has active industrial GHS classifications (H319).

Is Cyclododecane, 1-methoxy-1-methyl- used outside industrial chemicals?

Cyclododecane, 1-methoxy-1-methyl- also appears in cosmetics databases.