What is the NOAEL for Crocin?
Crocin has 4 NOAEL studies in the database. The lowest reported value is 877GWI46C2 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Crocin
Also known as: BRN 6473367, EINECS 255-881-6, alpha-Crocin, all-trans-Crocetin di-beta-D-gentiobiosyl ester, Crocetin bis(gentiobiosyl) ester
CAS 42553-65-1
Crocin (CAS 42553-65-1) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Crocin
CAS Number
42553-65-1
DTXSID
DTXSID7046172
Molecular Formula
C44H64O24
InChI Key
SEBIKDIMAPSUBY-RTJKDTQDSA-N
Monoisotopic Mass
976.378753
Synonyms
BRN 6473367EINECS 255-881-6alpha-Crocinall-trans-Crocetin di-beta-D-gentiobiosyl esterCrocetin bis(gentiobiosyl) ester
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
AntioxidantDye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 877GWI46C2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 877GWI46C2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 877GWI46C2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 877GWI46C2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Colorants
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CROCIN
ChEMBL Phase
3
Adverse Events
0
Bioactivity
2
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E164 — ADI: FOOD INGREDIENT mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Crocin?
Crocin appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Crocin used in cosmetics?
Yes, Crocin is also indexed as a cosmetic ingredient under the name CROCIN. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Crocin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Crocin used outside industrial chemicals?
Crocin also appears in cosmetics, pharmaceutical, food safety databases.