What is the NOAEL for C.I. Acid Blue 62?
C.I. Acid Blue 62 has 29 NOAEL studies in the database. The lowest reported value is DG356U29IU UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
C.I. Acid Blue 62
Also known as: 2-Anthracenesulfonic acid, 1-amino-4-(cyclohexylamino)-9,10-dihydro-9,10-dioxo-, monosodium salt, C.I. 62045, 2-Anthracenesulfonic acid, 1-amino-4-(cyclohexylamino)-9,10-dihydro-9,10-dioxo-, sodium salt (1:1), 1-Amino-4-cyclohexylaminoanthraquinone-2-sodium sulfonate, Lerui Acid Brilliant Blue P 3FRL (+15 more)
CAS 4368-56-3
C.I. Acid Blue 62 (CAS 4368-56-3) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS, ECHA REACH.
Cross-Vertical Regulatory Divergence
C.I. Acid Blue 62 is classified GHS CMR hazard (H319, H341, H412, H413) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
29
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
C.I. Acid Blue 62
CAS Number
4368-56-3
DTXSID
DTXSID3044673
Molecular Formula
C20H20N2O5S.Na
InChI Key
DJDYMAHXZBQZKH-UHFFFAOYSA-M
Synonyms
2-Anthracenesulfonic acid, 1-amino-4-(cyclohexylamino)-9,10-dihydro-9,10-dioxo-, monosodium saltC.I. 620452-Anthracenesulfonic acid, 1-amino-4-(cyclohexylamino)-9,10-dihydro-9,10-dioxo-, sodium salt (1:1)1-Amino-4-cyclohexylaminoanthraquinone-2-sodium sulfonateLerui Acid Brilliant Blue P 3FRLLissamine Blue 2BRMidlon Blue 2RNaphthazine Blue CRFFSodium 1-amino-4-(cyclohexylamino)-2-anthraquinonesulfonateVicoacid Blue 62Vopsider Blue AIRWeak Acid Brilliant Blue 2BR
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Europe; Personal care | European Commission | CosIng |
| Europe; Personal care; restricted | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 29 of 29 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| DG356U29IU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DG356U29IU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DG356U29IU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DG356U29IU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 100 | mg/kg bw/day | LOAEL | oral | rat | COSMOS_DB |
| 300 | mg/kg bw/day | LOAEL | oral | rat | COSMOS_DB |
| =53 | % | NOAEL | oral | mouse | SCCNFP_vision_codex |
| =53 | % | NOAEL | oral | mouse | SCCNFP_vision_codex |
| =53 | % | NOAEL | oral | mouse | SCCNFP_vision_codex |
| =53 | % | NOAEL | oral | mouse | SCCNFP_vision_codex |
| =160 | mg/kg | NOAEL | oral | rat | SCCS_vision_codex |
| =160 | mg/kg | NOAEL | oral | rat | SCCS_vision_codex |
| =160 | mg/kg | NOAEL | oral | rat | SCCS_vision_codex |
| =160 | mg/kg | NOAEL | oral | rat | SCCS_vision_codex |
| =300 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =300 | mg/kg bw/day | NOAEL | - | rat | SCCNFP_vision_codex |
| =300 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =300 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =300 | mg/kg bw/day | NOAEL | - | rat | SCCNFP_vision_codex |
| =300 | mg/kg bw/day | NOAEL | - | rat | SCCNFP_vision_codex |
| =300 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =300 | mg/kg bw/day | NOAEL | - | rat | SCCNFP_vision_codex |
| 300 | mg/kg bw/day | developmental toxicity | - | rat | UnifiedCodex:SCCNFP:beta.noael_studies |
| 300 | mg/kg bw/day | developmental toxicity | - | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 300 | mg/kg bw/day | developmental toxicity | - | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 53 | % | repeated dose toxicity | oral | mouse | UnifiedCodex:SCCNFP:beta.noael_studies |
| =160 | mg/kg | repeated dose toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| =160 | mg/kg | repeated dose toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| =160 | mg/kg | repeated dose toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
Showing 29 of 29 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium 1-amino-4-(cyclohexylamino)-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate | 224-460-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
SCCS Opinions
EU Scientific Committee opinions tied to the matched substance.
SOURCE
EU SCCS
1 opinions
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCP/0861/05 | 21 June 2005 | safe | 0.3% | sensitisation not excluded |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Colorants
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL606414
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
What regulatory lists include C.I. Acid Blue 62?
C.I. Acid Blue 62 appears on 3 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Europe; Personal care, Europe; Personal care; restricted. Source: EPA CPDat.
Is C.I. Acid Blue 62 used in cosmetics?
Yes, C.I. Acid Blue 62 is also indexed as a cosmetic ingredient under the name CI 62045. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for C.I. Acid Blue 62 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does C.I. Acid Blue 62 have different safety status in cosmetics vs industrial chemicals?
C.I. Acid Blue 62 is classified GHS CMR hazard (H319, H341, H412, H413) in the chemicals database but is restricted in EU cosmetics.
Is C.I. Acid Blue 62 used outside industrial chemicals?
C.I. Acid Blue 62 also appears in cosmetics, pharmaceutical databases.