What is the NOAEL for Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)-?
Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- has 5 NOAEL studies in the database. The lowest reported value is U6WSN5SQ1Z UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)-
Also known as: Zinc, bis(D-gluconato-kappaO1,kappaO2)-, (T-4)-, Bis(D-gluconato-O1,O2) zinc
CAS 4468-02-4
Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- (CAS 4468-02-4) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- is classified GHS Danger (H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)-
CAS Number
4468-02-4
DTXSID
DTXSID20894125
Molecular Formula
2C6H12O7.Zn
InChI Key
WHMDKBIGKVEYHS-IYEMJOQQSA-L
Monoisotopic Mass
456.045747
Synonyms
Zinc, bis(D-gluconato-kappaO1,kappaO2)-, (T-4)-Bis(D-gluconato-O1,O2) zinc
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
8 records
DeodorizerSoftener and conditionerBiocideFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; Pesticides | EPA | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| Europe; supplements | EU | CPCat |
| Europe; food_additive; supplements | EU | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| U6WSN5SQ1Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U6WSN5SQ1Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U6WSN5SQ1Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U6WSN5SQ1Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =50 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECOTOX |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Bis(D-gluconato-O1,O2)zinc | 224-736-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ZINC GLUCONATE
ChEMBL Phase
3
Adverse Events
766
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)-?
Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- appears on 6 regulatory/inventory lists including inert_ingredient; Pesticides, active_ingredient; animal_products; Europe; pharmaceutical; residue, Europe; supplements, and 3 more. Source: EPA CPDat.
Is Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- used in cosmetics?
Yes, Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- is also indexed as a cosmetic ingredient under the name Zinc Gluconate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Does Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- have different safety status in cosmetics vs industrial chemicals?
Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- is classified GHS Danger (H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Is Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- used outside industrial chemicals?
Zinc, bis(D-gluconato-κO1,κO2)-, (T-4)- also appears in cosmetics, pharmaceutical, food safety databases.