What is the NOAEL for (3-Acrylamidopropyl)trimethylammonium chloride?
(3-Acrylamidopropyl)trimethylammonium chloride has 6 NOAEL studies in the database. The lowest reported value is T8AN58F7LI UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
(3-Acrylamidopropyl)trimethylammonium chloride
CAS 45021-77-0
(3-Acrylamidopropyl)trimethylammonium chloride (CAS 45021-77-0) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
View cosmetic safety profile for Acrylamidopropyltrimonium Chloride →
Cross-Vertical Regulatory Divergence
(3-Acrylamidopropyl)trimethylammonium chloride is prohibited in EU cosmetics but has active industrial GHS classifications (H412).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
(3-Acrylamidopropyl)trimethylammonium chloride
CAS Number
45021-77-0
DTXSID
DTXSID20885891
Molecular Formula
C9H18N2O.ClH
InChI Key
OEIXGLMQZVLOQX-UHFFFAOYSA-N
Monoisotopic Mass
206.118591
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
No specific technical function
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| T8AN58F7LI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T8AN58F7LI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T8AN58F7LI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T8AN58F7LI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =3000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Trimethyl-3-[(1-oxoallyl)amino]propylammonium chloride | 256-181-3 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
Is (3-Acrylamidopropyl)trimethylammonium chloride used in cosmetics?
Yes, (3-Acrylamidopropyl)trimethylammonium chloride is also indexed as a cosmetic ingredient under the name Acrylamidopropyltrimonium Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (3-Acrylamidopropyl)trimethylammonium chloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does (3-Acrylamidopropyl)trimethylammonium chloride have different safety status in cosmetics vs industrial chemicals?
(3-Acrylamidopropyl)trimethylammonium chloride is prohibited in EU cosmetics but has active industrial GHS classifications (H412).
Is (3-Acrylamidopropyl)trimethylammonium chloride used outside industrial chemicals?
(3-Acrylamidopropyl)trimethylammonium chloride also appears in cosmetics databases.