Acrylamidopropyltrimonium Chloride
INCI: ACRYLAMIDOPROPYLTRIMONIUM CHLORIDE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Acrylamidopropyltrimonium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 200 mg/kg bw/day | oral | dog | oral | REACH |
| NOAEL | 3000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Cationic charge may cause irritation at high concentrations; residual acrylamide monomer must be controlled
Frequently Asked Questions
Is Acrylamidopropyltrimonium Chloride safe in cosmetics?
Cationic charge may cause irritation at high concentrations; residual acrylamide monomer must be controlled The EU classifies Acrylamidopropyltrimonium Chloride as "prohibited". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Acrylamidopropyltrimonium Chloride allowed in the EU?
Acrylamidopropyltrimonium Chloride EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Acrylamidopropyltrimonium Chloride do in cosmetics?
Acrylamidopropyltrimonium Chloride functions as: Antistatic, hair fixing. It is classified as a cosmetic ingredient in our database. CAS number: 45021-77-0.
What is the Margin of Safety for Acrylamidopropyltrimonium Chloride?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Acrylamidopropyltrimonium Chloride?
The NOAEL (No Observed Adverse Effect Level) for Acrylamidopropyltrimonium Chloride is 200 mg/kg bw/day based on a oral study via oral route in dog. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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