Also known as: Hexahydro-1,3,5-tris(hydroxyethyl)-s- triazine, Grotan BK, Hexahydro-1,3,5-tri(2-hydroxyethyl)-s-triazine, s-Triazine-1,3,5(2H,4H,6H)-triethanol, N,N',N''-Tris(2-hydroxyethyl)hexahydro-s-triazine (+15 more)
CAS 4719-04-4
Triazinetriethanol (CAS 4719-04-4) is a chemical substance with GHS signal word Warning; key hazard signal: H302; H317. Key regulatory status: REACH registered, 19 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Tris(N-Hydroxyethyl) Hexahydrotriazine →
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Acute Tox. 4 *; Skin Sens. 1 | H302; H317 | GHS07 | Warning |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.2 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| OU2JEB22IE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OU2JEB22IE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OU2JEB22IE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OU2JEB22IE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =763 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =5 | mg/kg bw/day | LEL | dermal | Rat | ToxValDB_ToxRefDB |
| =5 | mg/kg bw/day | LEL | dermal | rat (sprague dawley; CD(SD)BR) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =100 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ToxRefDB |
| =100 | mg/kg bw/day | LEL | oral | rat (sprague dawley; CD(SD)BR) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =500 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ToxRefDB |
| =500 | mg/kg bw/day | LEL | oral | rat | ToxRefDB_ToxRefDB_v3_pod.csv |
| >750 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ToxRefDB |
| =50 | mg/kg bw/day | LOAEL | dermal | Rat | ToxValDB_ToxRefDB |
| =50 | mg/kg bw/day | LOAEL | dermal | rat (sprague dawley; CD(SD)BR) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =750 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ToxRefDB |
| =750 | mg/kg bw/day | LOAEL | oral | rat | ToxRefDB_ToxRefDB_v3_pod.csv |
| =20 | % | LOEL | dermal | Mouse | ToxValDB_ECOTOX |
| >- | mg/kg bw/day | NEL | dermal | rat (sprague dawley; CD(SD)BR) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =50 | mg/kg bw/day | NEL | oral | Rat | ToxValDB_ToxRefDB |
| =50 | mg/kg bw/day | NEL | oral | rat (sprague dawley; CD(SD)BR) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =250 | mg/kg bw/day | NEL | oral | Rat | ToxValDB_ToxRefDB |
| =250 | mg/kg bw/day | NEL | oral | rat | ToxRefDB_ToxRefDB_v3_pod.csv |
Showing 24 of 24 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,2',2''-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol | 225-208-0 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Triazinetriethanol (CAS 4719-04-4) is classified under EU CLP Annex VI as Acute Tox. 4 *; Skin Sens. 1 with signal word Warning. Hazard statements: H302; H317. Source: EU CLP Annex VI (ECHA).
Triazinetriethanol has 24 NOAEL studies in the database. The lowest reported value is 0.2 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
Triazinetriethanol appears on 2 regulatory/inventory lists including active_ingredient; Europe; Pesticides, active_ingredient; Pesticides. Source: EPA CPDat.
Yes, Triazinetriethanol is also indexed as a cosmetic ingredient under the name Tris(N-Hydroxyethyl) Hexahydrotriazine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Triazinetriethanol also appears in cosmetics, pharmaceutical databases.