What is the NOAEL for Naringenin?
Naringenin has 4 NOAEL studies in the database. The lowest reported value is HN5425SBF2 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Naringenin
Also known as: (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, EINECS 207-550-2, Narigenin, 5,7,4'-Trihydroxyflavanone, UNII-HN5425SBF2 (+6 more)
CAS 480-41-1
Naringenin (CAS 480-41-1) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Naringenin
CAS Number
480-41-1
DTXSID
DTXSID1022392
Molecular Formula
C15H12O5
InChI Key
FTVWIRXFELQLPI-ZDUSSCGKSA-N
Monoisotopic Mass
272.068473
Synonyms
(S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-oneEINECS 207-550-2Narigenin5,7,4'-TrihydroxyflavanoneUNII-HN5425SBF2(-)-(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one(2S)-Naringenin(S)-2,3-dihydo-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-oneAsahinapelargidanon
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| HN5425SBF2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HN5425SBF2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HN5425SBF2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HN5425SBF2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
NARINGENIN
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
9
Frequently Asked Questions
What regulatory lists include Naringenin?
Naringenin appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Naringenin used in cosmetics?
Yes, Naringenin is also indexed as a cosmetic ingredient under the name NARINGENIN. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Naringenin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Naringenin used outside industrial chemicals?
Naringenin also appears in cosmetics, pharmaceutical databases.