What is the NOAEL for 2-Phenoxyethyl acrylate?
2-Phenoxyethyl acrylate has 6 NOAEL studies in the database. The lowest reported value is 12 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Phenoxyethyl acrylate
Also known as: Ethylene glycol phenyl ether acrylate, 2-Propenoic acid, 2-phenoxyethyl ester, Ethylene glycol monophenyl ether monoacrylate, Acrylic acid, 2-phenoxyethyl ester, BRN 2102773 (+7 more)
CAS 48145-04-6
2-Phenoxyethyl acrylate (CAS 48145-04-6) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
2-Phenoxyethyl acrylate is classified GHS CMR hazard (H315, H317, H319, H361, H411) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
2-Phenoxyethyl acrylate
CAS Number
48145-04-6
DTXSID
DTXSID4040715
Molecular Formula
C11H12O3
InChI Key
RZVINYQDSSQUKO-UHFFFAOYSA-N
Monoisotopic Mass
192.078644
Synonyms
Ethylene glycol phenyl ether acrylate2-Propenoic acid, 2-phenoxyethyl esterEthylene glycol monophenyl ether monoacrylateAcrylic acid, 2-phenoxyethyl esterBRN 2102773Chemlink 160Ebecryl 110EINECS 256-360-6Light ester PO-A2-Phenoxyethanol acrylatePhenoxyethyl acrylatePhenyl cellosolve acrylate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
17 records
Viscosity modifierChemical reaction regulator
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =77 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =12 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| N95C96I48M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N95C96I48M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N95C96I48M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N95C96I48M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-phenoxyethyl acrylate | 256-360-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1596010
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
Is 2-Phenoxyethyl acrylate used in cosmetics?
Yes, 2-Phenoxyethyl acrylate is also indexed as a cosmetic ingredient under the name Phenoxyethyl Acrylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Phenoxyethyl acrylate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-Phenoxyethyl acrylate have different safety status in cosmetics vs industrial chemicals?
2-Phenoxyethyl acrylate is classified GHS CMR hazard (H315, H317, H319, H361, H411) in the chemicals database but is allowed in EU cosmetics.
Is 2-Phenoxyethyl acrylate used outside industrial chemicals?
2-Phenoxyethyl acrylate also appears in cosmetics, pharmaceutical databases.