Is Phenoxyethyl Acrylate safe in cosmetics?
Phenoxyethyl Acrylate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Phenoxyethyl Acrylate
Also known as: Ethylene glycol phenyl ether acrylate, 2-Propenoic acid, 2-phenoxyethyl ester, Ethylene glycol monophenyl ether monoacrylate, Acrylic acid, 2-phenoxyethyl ester, BRN 2102773 (+6 more)
INCI: PHENOXYETHYL ACRYLATE
Phenoxyethyl Acrylate (CAS 48145-04-6) is a cosmetic cosmetic ingredient functioning as Film former / monomer for cosmetic polymers. NOAEL 300 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 48145-04-6 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Phenoxyethyl Acrylate is classified GHS CMR hazard (H315, H317, H319, H361, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Film former / monomer for cosmetic polymers
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-phenoxyethyl prop-2-enoate
InChIKey
RZVINYQDSSQUKO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR reviewed acrylates group — safe when formulated to avoid irritation; for monomers, directions to avoid skin contact recommended
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Phenoxyethyl Acrylate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Phenoxyethyl Acrylate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Chemical reaction regulator
Viscosity modifier
Expert Verdict
Expert safety assessment and concern-level summary for Phenoxyethyl Acrylate.
Known Synonyms
Ethylene glycol phenyl ether acrylate
2-Propenoic acid, 2-phenoxyethyl ester
Ethylene glycol monophenyl ether monoacrylate
Acrylic acid, 2-phenoxyethyl ester
BRN 2102773
Chemlink 160
Ebecryl 110
EINECS 256-360-6
Light ester PO-A
2-Phenoxyethanol acrylate
Phenyl cellosolve acrylate
Chemical Function
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1596010
Frequently Asked Questions
Is Phenoxyethyl Acrylate allowed in the EU?
Phenoxyethyl Acrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phenoxyethyl Acrylate do in cosmetics?
Phenoxyethyl Acrylate functions as: Film former / monomer for cosmetic polymers. It is classified as a cosmetic ingredient in our database. CAS number: 48145-04-6.
Is Phenoxyethyl Acrylate used outside cosmetics?
Phenoxyethyl Acrylate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Phenoxyethyl Acrylate have different safety status in cosmetics vs industrial chemicals?
Phenoxyethyl Acrylate is classified GHS CMR hazard (H315, H317, H319, H361, H411) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Phenoxyethyl Acrylate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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