What is the NOAEL for Butyrophenone?
Butyrophenone has 4 NOAEL studies in the database. The lowest reported value is 186I11WB5B UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Butyrophenone
Also known as: EINECS 207-799-7, UNII-186I11WB5B
CAS 495-40-9
Butyrophenone (CAS 495-40-9) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Butyrophenone is classified GHS Danger (H317, H318) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
Butyrophenone
CAS Number
495-40-9
DTXSID
DTXSID3047059
Molecular Formula
C10H12O
InChI Key
FFSAXUULYPJSKH-UHFFFAOYSA-N
Monoisotopic Mass
148.088815
Synonyms
EINECS 207-799-7UNII-186I11WB5B
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 186I11WB5B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 186I11WB5B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 186I11WB5B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 186I11WB5B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
BUTYROPHENONE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Butyrophenone?
Butyrophenone appears on 3 regulatory/inventory lists including Europe, IFRA Transparency, consumer_product. Source: EPA CPDat.
Is Butyrophenone used in cosmetics?
Yes, Butyrophenone is also indexed as a cosmetic ingredient under the name Butyrophenone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Butyrophenone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Butyrophenone have different safety status in cosmetics vs industrial chemicals?
Butyrophenone is classified GHS Danger (H317, H318) in the chemicals database but is allowed in EU cosmetics.
Is Butyrophenone used outside industrial chemicals?
Butyrophenone also appears in cosmetics, pharmaceutical, cannabis databases.