Butyrophenone

INCI: BUTYROPHENONE

CAS Number
495-40-9
Function
Synthetic aromatic ketone used in fragrance chemistry
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not established

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Synthetic aromatic ketone with no established cosmetic function; combustible with incomplete toxicological data and pharmacological activity concerns requiring comprehensive safety assessment before cosmetic use.

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Concern Level: High

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is Butyrophenone safe in cosmetics?

Synthetic aromatic ketone with no established cosmetic function; combustible with incomplete toxicological data and pharmacological activity concerns requiring comprehensive safety assessment before cosmetic use. The EU classifies Butyrophenone as "permitted". Safety rating: POOR.

Is Butyrophenone allowed in the EU?

Butyrophenone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Butyrophenone do in cosmetics?

Butyrophenone functions as: Synthetic aromatic ketone used in fragrance chemistry. It is classified as a cosmetic ingredient in our database. CAS number: 495-40-9.

What is the Margin of Safety for Butyrophenone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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