NOAEL Data REACH Registered Cosmetic Ingredient

(2-(Methacryloyloxy)ethyl)trimethylammonium chloride

Also known as: Ethanaminium, N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propenyl)oxy]-, chloride, EINECS 225-733-5, UNII-PP88R88K3O

CAS 5039-78-1

(2-(Methacryloyloxy)ethyl)trimethylammonium chloride (CAS 5039-78-1) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Methacryloyloxyethyltrimonium Chloride →

SOURCE noael studies public
NOAEL studies
6
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 9 fields
Name
(2-(Methacryloyloxy)ethyl)trimethylammonium chloride
CAS Number
5039-78-1
DTXSID
DTXSID3027586
Molecular Formula
C9H18NO2.ClH
InChI Key
RRHXZLALVWBDKH-UHFFFAOYSA-M
Monoisotopic Mass
208.110432
Synonyms
Ethanaminium, N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propenyl)oxy]-, chlorideEINECS 225-733-5UNII-PP88R88K3O

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies
ValueUnitEndpointRouteSpeciesSource
PP88R88K3OUNIIFDA UNII substance identifier--openFDA substances
PP88R88K3OUNIIFDA UNII substance identifier--openFDA substances
PP88R88K3OUNIIFDA UNII substance identifier--openFDA substances
PP88R88K3OUNIIFDA UNII substance identifier--openFDA substances
>2000mg/kg bwLD50oralRatNTP_ICE_acute_oral
=1000mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered[2-(methacryloyloxy)ethyl]trimethylammonium chloride225-733-5ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3187310
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for (2-(Methacryloyloxy)ethyl)trimethylammonium chloride?

(2-(Methacryloyloxy)ethyl)trimethylammonium chloride has 6 NOAEL studies in the database. The lowest reported value is PP88R88K3O UNII. Source: openFDA substances.

Is (2-(Methacryloyloxy)ethyl)trimethylammonium chloride used in cosmetics?

Yes, (2-(Methacryloyloxy)ethyl)trimethylammonium chloride is also indexed as a cosmetic ingredient under the name Methacryloyloxyethyltrimonium Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for (2-(Methacryloyloxy)ethyl)trimethylammonium chloride come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is (2-(Methacryloyloxy)ethyl)trimethylammonium chloride used outside industrial chemicals?

(2-(Methacryloyloxy)ethyl)trimethylammonium chloride also appears in cosmetics, pharmaceutical databases.