Is Methacryloyloxyethyltrimonium Chloride safe in cosmetics?
Methacryloyloxyethyltrimonium Chloride has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methacryloyloxyethyltrimonium Chloride
Also known as: Ethanaminium, N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propenyl)oxy]-, chloride, EINECS 225-733-5, UNII-PP88R88K3O
INCI: USED AS A MONOMER COMPONENT; APPEARS IN COPOLYMER INCI NAMES (E.G., ACRYLAMIDE/METHACRYLOYLOXYETHYLTRIMONIUM CHLORIDE COPOLYMER, CAS 35429-19-7)
Methacryloyloxyethyltrimonium Chloride (CAS 5039-78-1) is a cosmetic cosmetic ingredient functioning as Cationic monomer for synthesis of conditioning/antistatic polymers; quaternary. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 5039-78-1 →
Auto-generated CPSR Part A draft with source citations
Function
Cationic monomer for synthesis of conditioning/antistatic polymers; quaternary ammonium functionality provides positive charge for hair substantivity
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
trimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium chloride
InChIKey
RRHXZLALVWBDKH-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - not specifically restricted; copolymers containing this monomer have been reviewed
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methacryloyloxyethyltrimonium Chloride.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expert Verdict
Expert safety assessment and concern-level summary for Methacryloyloxyethyltrimonium Chloride.
Known Synonyms
Ethanaminium, N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propenyl)oxy]-, chloride
EINECS 225-733-5
UNII-PP88R88K3O
Chemical Function
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3187310
Frequently Asked Questions
Is Methacryloyloxyethyltrimonium Chloride allowed in the EU?
Methacryloyloxyethyltrimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methacryloyloxyethyltrimonium Chloride do in cosmetics?
Methacryloyloxyethyltrimonium Chloride functions as: Cationic monomer for synthesis of conditioning/antistatic polymers; quaternary ammonium functionality provides positive charge for hair substantivity. It is classified as a cosmetic ingredient in our database. CAS number: 5039-78-1.
Is Methacryloyloxyethyltrimonium Chloride used outside cosmetics?
Methacryloyloxyethyltrimonium Chloride also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Methacryloyloxyethyltrimonium Chloride compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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