NOAEL Data REACH Registered Cosmetic Ingredient

Trimethyl isopropyl butanamide

Also known as: Butanamide, N,2,3-trimethyl-2-(1-methylethyl)-, EINECS 256-974-4, Methyl diisopropyl propionamide, N,2,3-Trimethyl-2-isopropylbutanamide, N,2,3-Trimethyl-2-(1-methylethyl)butanamide (+1 more)

CAS 51115-67-4

Trimethyl isopropyl butanamide (CAS 51115-67-4) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Methyl Diisopropyl Propionamide →

SOURCE NOAEL studies
NOAEL studies
6
SOURCE Chemical inventory jurisdictions
Regulatory lists
4
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Trimethyl isopropyl butanamide
CAS Number
51115-67-4
DTXSID
DTXSID40199124
Molecular Formula
C10H21NO
InChI Key
RWAXQWRDVUOOGG-UHFFFAOYSA-N
Monoisotopic Mass
171.162314
Synonyms
Butanamide, N,2,3-trimethyl-2-(1-methylethyl)-EINECS 256-974-4Methyl diisopropyl propionamideN,2,3-Trimethyl-2-isopropylbutanamideN,2,3-Trimethyl-2-(1-methylethyl)butanamideUNII-6QOP5A9489

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records
DeodorizerFragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
EuropeEuropean CommissionFl@vis
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
Canada; Personal care; Substances in PCP - Canada (4/2014)Government of CanadaCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies
ValueUnitEndpointRouteSpeciesSource
6QOP5A9489UNIIFDA UNII substance identifier--openFDA substances
6QOP5A9489UNIIFDA UNII substance identifier--openFDA substances
6QOP5A9489UNIIFDA UNII substance identifier--openFDA substances
6QOP5A9489UNIIFDA UNII substance identifier--openFDA substances
=5mg/kg bw/dayNOELoralRatEFSA
=5mg/kg bw/dayNOELoral: feedRatEFSA

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records
StatusNameEC NumberLink
Registered2-isopropyl-N,2,3-trimethylbutyramide256-974-4ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the introduction volume of the chemical exceeds 1 tonne per annum b. the chemical is introduced in products other than toothpastes, mouthwashes, or dental floss c. the concentration of the chemical exceeds or is intended to exceed 0.052% in toothpastes, 0.009% in mouthwashes or 0.045 mg/inch of floss in dental floss 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Trimethyl isopropyl butanamide?

Trimethyl isopropyl butanamide has 6 NOAEL studies in the database. The lowest reported value is 6QOP5A9489 UNII. Source: openFDA substances.

What regulatory lists include Trimethyl isopropyl butanamide?

Trimethyl isopropyl butanamide appears on 4 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.

Is Trimethyl isopropyl butanamide used in cosmetics?

Yes, Trimethyl isopropyl butanamide is also indexed as a cosmetic ingredient under the name Methyl Diisopropyl Propionamide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Trimethyl isopropyl butanamide come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Trimethyl isopropyl butanamide used outside industrial chemicals?

Trimethyl isopropyl butanamide also appears in cosmetics, cannabis databases.