Methyl Diisopropyl Propionamide

INCI: METHYL DIISOPROPYL PROPIONAMIDE

CAS Number
51115-67-4
Function
Cooling agent / sensory modifier - provides long-lasting refreshing sensation without menthol
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific prohibition; allowed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low odor and low volatility; free of listed EU fragrance allergens; generally well-tolerated on sensitive skin areas. Marketed as "Fresh'in" by Minasolve; crystalline powder; cooling effect ranges from subtle freshness to powerful chill; not derived from menthol; melting point 58-61 °C

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Methyl Diisopropyl Propionamide safe in cosmetics?

Low odor and low volatility; free of listed EU fragrance allergens; generally well-tolerated on sensitive skin areas. Marketed as "Fresh'in" by Minasolve; crystalline powder; cooling effect ranges from subtle freshness to powerful chill; not derived from menthol; melting point 58-61 °C The EU classifies Methyl Diisopropyl Propionamide as "permitted". Safety rating: MODERATE.

Is Methyl Diisopropyl Propionamide allowed in the EU?

Methyl Diisopropyl Propionamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Diisopropyl Propionamide do in cosmetics?

Methyl Diisopropyl Propionamide functions as: Cooling agent / sensory modifier - provides long-lasting refreshing sensation without menthol. It is classified as a cosmetic ingredient in our database. CAS number: 51115-67-4.

What is the Margin of Safety for Methyl Diisopropyl Propionamide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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