Also known as: Morpholine, 4-(1-oxo-2-propenyl)-, 4-(1-Oxo-2-propenyl)morpholine, 1-(Morpholin-4-yl)prop-2-en-1-one, 2-Propen-1-one, 1-(4-morpholinyl)-, UNII-K0Y58P61JA
CAS 5117-12-4
4-(1-Oxo-2-propenyl)-morpholine (CAS 5117-12-4) is a chemical substance with GHS signal word Danger; key hazard signal: H302; H373 **; H318; H317. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
4-(1-Oxo-2-propenyl)-morpholine is classified GHS Danger (H302, H373, H318, H317) in the chemicals database but is allowed in EU cosmetics.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Acute Tox. 4 *; STOT RE 2 *; Eye Dam. 1; Skin Sens. 1 | H302; H373 **; H318; H317 | GHS07; GHS08; GHS05 | Danger |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Cons electronics mech appliances and machinery; detected; Europe | Danish EPA | Danish EPA |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =2.65 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| =132.2 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| K0Y58P61JA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 3 of 3 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 4-(1-oxo-2-propenyl)-morpholine | 418-140-1 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
4-(1-Oxo-2-propenyl)-morpholine (CAS 5117-12-4) is classified under EU CLP Annex VI as Acute Tox. 4 *; STOT RE 2 *; Eye Dam. 1; Skin Sens. 1 with signal word Danger. Hazard statements: H302; H373 **; H318; H317. Source: EU CLP Annex VI (ECHA).
4-(1-Oxo-2-propenyl)-morpholine has 3 NOAEL studies in the database. The lowest reported value is 2.65 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
4-(1-Oxo-2-propenyl)-morpholine appears on 1 regulatory/inventory list including Cons electronics mech appliances and machinery; detected; Europe. Source: EPA CPDat.
Yes, 4-(1-Oxo-2-propenyl)-morpholine is also indexed as a cosmetic ingredient under the name Acryloyl Morpholine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
4-(1-Oxo-2-propenyl)-morpholine is classified GHS Danger (H302, H373, H318, H317) in the chemicals database but is allowed in EU cosmetics.
4-(1-Oxo-2-propenyl)-morpholine also appears in cosmetics, pharmaceutical databases.