What is the NOAEL for 3-beta-Hydroxy-5-alpha-pregnan-20-one?
3-beta-Hydroxy-5-alpha-pregnan-20-one has 4 NOAEL studies in the database. The lowest reported value is 3P8Z6V53MU UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3-beta-Hydroxy-5-alpha-pregnan-20-one
Also known as: 5alpha-Pregnan-20-one, 3beta-hydroxy-, Pregnan-20-one, 3-hydroxy-, (3-beta,5-alpha)-, Allopregnanolone, Isopregnanolone
CAS 516-55-2
3-beta-Hydroxy-5-alpha-pregnan-20-one (CAS 516-55-2) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
3-beta-Hydroxy-5-alpha-pregnan-20-one
CAS Number
516-55-2
DTXSID
DTXSID001023710
Molecular Formula
C21H34O2
InChI Key
AURFZBICLPNKBZ-FZCSVUEKSA-N
Monoisotopic Mass
318.25588
Synonyms
5alpha-Pregnan-20-one, 3beta-hydroxy-Pregnan-20-one, 3-hydroxy-, (3-beta,5-alpha)-AllopregnanoloneIsopregnanolone
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 3P8Z6V53MU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3P8Z6V53MU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3P8Z6V53MU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3P8Z6V53MU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SEPRANOLONE
ChEMBL Phase
2
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
Is 3-beta-Hydroxy-5-alpha-pregnan-20-one used in cosmetics?
Yes, 3-beta-Hydroxy-5-alpha-pregnan-20-one is also indexed as a cosmetic ingredient under the name Pregnadienol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-beta-Hydroxy-5-alpha-pregnan-20-one come from?
Safety data is sourced from EPA ToxValDB, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-beta-Hydroxy-5-alpha-pregnan-20-one used outside industrial chemicals?
3-beta-Hydroxy-5-alpha-pregnan-20-one also appears in cosmetics, pharmaceutical databases.