Pregnadienol

INCI: PREGNADIENOL

CAS Number
516-55-2
Function
Fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction for cosmetic fragrance use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Steroidal pregnane derivative with potential endocrine activity and limited safety data for cosmetic use; fragrance use likely at very low concentrations, but a CPSR should address hormonal activity potential

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Concern Level: Moderate

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Pregnadienol safe in cosmetics?

Steroidal pregnane derivative with potential endocrine activity and limited safety data for cosmetic use; fragrance use likely at very low concentrations, but a CPSR should address hormonal activity potential The EU classifies Pregnadienol as "permitted". Safety rating: MODERATE.

Is Pregnadienol allowed in the EU?

Pregnadienol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pregnadienol do in cosmetics?

Pregnadienol functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 516-55-2.

What is the Margin of Safety for Pregnadienol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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