What is the NOAEL for Matrine?
Matrine has 4 NOAEL studies in the database. The lowest reported value is N390W430AC UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Matrine
Also known as: (+)-Matrine, Matridin-15-one, 1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, (7aS,13aR,13bR,13cS)-, (7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, NSC 318810 (+6 more)
CAS 519-02-8
Matrine (CAS 519-02-8) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
NOAEL studies
NOAEL studies
4
SOURCE
Chemical inventory jurisdictions
Regulatory lists
0
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Matrine
CAS Number
519-02-8
DTXSID
DTXSID00274188
Molecular Formula
C15H24N2O
InChI Key
ZSBXGIUJOOQZMP-JLNYLFASSA-N
Monoisotopic Mass
248.188863
Synonyms
(+)-MatrineMatridin-15-one1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, (7aS,13aR,13bR,13cS)-(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-oneNSC 318810Vegardalpha-Matrine5-24-02-00301BRN 0085851Matrene, (+)-NSC 146051
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
AntioxidantSoftener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| N390W430AC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N390W430AC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N390W430AC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N390W430AC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
MATRINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
4
Frequently Asked Questions
Is Matrine used in cosmetics?
Yes, Matrine is also indexed as a cosmetic ingredient under the name Matrine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Matrine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Matrine used outside industrial chemicals?
Matrine also appears in cosmetics, pharmaceutical databases.