Regulatory Status
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Safety Data
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Expert Verdict
Quinolizidine alkaloid from Sophora flavescens - potentially toxic at high oral doses. Limited dedicated cosmetic safety assessment. Should be used at low concentrations in topical products. Heavy metal and microbial contamination must be controlled in raw material sourcing. Extracted from Sophora flavescens root. Demonstrates anti-inflammatory (inhibits TNF-ฮฑ, IL-6), antibacterial (against P. acnes), and tyrosinase-inhibiting (brightening) activity. Also used in agricultural pest control and...
Frequently Asked Questions
Is Matrine safe in cosmetics?
Quinolizidine alkaloid from Sophora flavescens - potentially toxic at high oral doses. Limited dedicated cosmetic safety assessment. Should be used at low concentrations in topical products. Heavy metal and microbial contamination must be controlled in raw material sourcing. Extracted from Sophora flavescens root. Demonstrates anti-inflammatory (inhibits TNF-ฮฑ, IL-6), antibacterial (against P. acnes), and tyrosinase-inhibiting (brightening) activity. Also used in agricultural pest control and... The EU classifies Matrine as "permitted". Safety rating: MODERATE.
Is Matrine allowed in the EU?
Matrine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Matrine do in cosmetics?
Matrine functions as: Antioxidant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 519-02-8.
What is the Margin of Safety for Matrine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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