What is the NOAEL for Diosmetin?
Diosmetin has 4 NOAEL studies in the database. The lowest reported value is TWZ37241OT UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Diosmetin
Also known as: EINECS 208-291-8, 5,7,3'-Trihydroxy-4'-methoxyflavone, UNII-TWZ37241OT, 3',5,7-trihydroxy-4'-methoxyflavone, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone (+2 more)
CAS 520-34-3
Diosmetin (CAS 520-34-3) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Diosmetin
CAS Number
520-34-3
DTXSID
DTXSID80199966
Molecular Formula
C16H12O6
InChI Key
MBNGWHIJMBWFHU-UHFFFAOYSA-N
Monoisotopic Mass
300.063388
Synonyms
EINECS 208-291-85,7,3'-Trihydroxy-4'-methoxyflavoneUNII-TWZ37241OT3',5,7-trihydroxy-4'-methoxyflavone5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyroneLuteolin 4'-methyl etherSalinigricoflavonol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| TWZ37241OT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TWZ37241OT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TWZ37241OT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TWZ37241OT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone | 208-291-8 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
DIOSMETIN
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
10
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Diosmetin?
Diosmetin appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Diosmetin used in cosmetics?
Yes, Diosmetin is also indexed as a cosmetic ingredient under the name Diosmetin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Diosmetin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Diosmetin used outside industrial chemicals?
Diosmetin also appears in cosmetics, pharmaceutical, cannabis databases.