Regulatory Status
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Safety Data
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Expert Verdict
Well-characterized as pharmaceutical metabolite of diosmin but limited cosmetic-specific safety studies; weak TrkB receptor agonist activity—assess for unintended bioactivity at use levels; no CIR monograph.
Frequently Asked Questions
Is Diosmetin safe in cosmetics?
Well-characterized as pharmaceutical metabolite of diosmin but limited cosmetic-specific safety studies; weak TrkB receptor agonist activity—assess for unintended bioactivity at use levels; no CIR monograph. The EU classifies Diosmetin as "permitted". Safety rating: GOOD.
Is Diosmetin allowed in the EU?
Diosmetin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diosmetin do in cosmetics?
Diosmetin functions as: Skin conditioning, antioxidant (O-methylated flavone; aglycone of diosmin). It is classified as a cosmetic ingredient in our database. CAS number: 520-34-3.
What is the Margin of Safety for Diosmetin?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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