NOAEL Data REACH Registered Cosmetic Ingredient

Tetramethylol acetylenediurea

Also known as: Glycoluril, 1,3,4,6-tetrakis(hydroxymethyl)-, Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-, 2,4,6,8-Tetrakis(hydroxymethyl)glycoluril, EINECS 226-408-0, Fixapret 140 (+7 more)

CAS 5395-50-6

Tetramethylol acetylenediurea (CAS 5395-50-6) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Tetramethylolglycoluril →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields
Name
Tetramethylol acetylenediurea
CAS Number
5395-50-6
DTXSID
DTXSID8063830
Molecular Formula
C8H14N4O6
InChI Key
UUGLSEIATNSHRI-UHFFFAOYSA-N
Monoisotopic Mass
262.091334
Synonyms
Glycoluril, 1,3,4,6-tetrakis(hydroxymethyl)-Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-2,4,6,8-Tetrakis(hydroxymethyl)glycolurilEINECS 226-408-0Fixapret 140NSC 3319NSC 67452Tetrakis(hydroxymethyl)glycolurilN,N',N'',N'''-Tetrakis(hydroxymethyl)glycolurilTetramethylol acetylene diurieneUNII-3BH30G5P9HTetramethylolglycoluril

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Biocide

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
active_ingredient; Europe; PesticidesCommission of the European CommunitiesCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
3BH30G5P9HUNIIFDA UNII substance identifier--openFDA substances
3BH30G5P9HUNIIFDA UNII substance identifier--openFDA substances
3BH30G5P9HUNIIFDA UNII substance identifier--openFDA substances
3BH30G5P9HUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredTetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2,5(1H,3H)-dione226-408-0ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Tetramethylol acetylenediurea?

Tetramethylol acetylenediurea has 4 NOAEL studies in the database. The lowest reported value is 3BH30G5P9H UNII. Source: openFDA substances.

What regulatory lists include Tetramethylol acetylenediurea?

Tetramethylol acetylenediurea appears on 1 regulatory/inventory list including active_ingredient; Europe; Pesticides. Source: EPA CPDat.

Is Tetramethylol acetylenediurea used in cosmetics?

Yes, Tetramethylol acetylenediurea is also indexed as a cosmetic ingredient under the name Tetramethylolglycoluril. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Tetramethylol acetylenediurea come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Tetramethylol acetylenediurea used outside industrial chemicals?

Tetramethylol acetylenediurea also appears in cosmetics databases.