What is the NOAEL for Thimerosal?
Thimerosal has 28 NOAEL studies in the database. The lowest reported value is 2225PI3MOV UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Thimerosal
Also known as: ((o-Carboxyphenyl)thio)ethylmercury sodium salt, Merthiolate, Mercurate(1-), ethyl[2-(mercapto-.kappa.S)benzoato(2-)-.kappa.O]-, sodium (1:1), Caswell No. 766, EINECS 200-210-4 (+15 more)
CAS 54-64-8
Thimerosal (CAS 54-64-8) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
Thimerosal is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H317, H320, H341, H351, H360, H371, H372).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
28
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Thimerosal
CAS Number
54-64-8
DTXSID
DTXSID3025540
Molecular Formula
C7H6O2S.C2H5.Hg.Na
InChI Key
RTKIYNMVFMVABJ-UHFFFAOYSA-L
Synonyms
((o-Carboxyphenyl)thio)ethylmercury sodium saltMerthiolateMercurate(1-), ethyl[2-(mercapto-.kappa.S)benzoato(2-)-.kappa.O]-, sodium (1:1)Caswell No. 766EINECS 200-210-4EPA Pesticide Chemical Code 078901EstivinEthyl (sodium o-mercaptobenzoato)mercuryEthylmercurithiosalicyclic acid, sodium saltEthylmercurithiosalicylic acid sodium saltMercurate(1-), ethyl(2-mercaptobenzoate(2-)-O,S)-, sodium saltMercurate(1-), ethyl(o-mercaptobenzoato(2-))-, sodium
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Preservative
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| pharmaceutical | US International Trade Commission | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 28 of 28 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 2225PI3MOV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2225PI3MOV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2225PI3MOV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2225PI3MOV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.1 | ppm | NOAEL | - | - | SCCS_vision_codex |
| =0.1 | ppm | NOAEL | - | - | SCCS_vision_codex |
| =0.1 | ppm | NOAEL | - | - | SCCS_vision_codex |
| =0.1 | ppm | NOAEL | - | - | SCCS_vision_codex |
| =0.4 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =0.4 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =0.4 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =0.4 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =3.4 | - | NOAEL | oral | human | SCCS_vision_codex |
| =3.4 | - | NOAEL | oral | human | SCCS_vision_codex |
| =3.4 | - | NOAEL | oral | human | SCCS_vision_codex |
| =3.4 | - | NOAEL | oral | human | SCCS_vision_codex |
| =5 | % | NOAEL | oral | rat | SCCS_vision_codex |
| =5 | % | NOAEL | oral | rat | SCCS_vision_codex |
| =5 | % | NOAEL | oral | rat | SCCS_vision_codex |
| =5 | % | NOAEL | oral | rat | SCCS_vision_codex |
| =1686 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =1686 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =1686 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =1686 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =2015 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =2015 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =2015 | - | NOAEL | oral | rat | SCCS_vision_codex |
| =2015 | - | NOAEL | oral | rat | SCCS_vision_codex |
Showing 28 of 28 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Preservative
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
thiomersal
ChEMBL Phase
Not listed
Adverse Events
20
Bioactivity
21
Frequently Asked Questions
What regulatory lists include Thimerosal?
Thimerosal appears on 4 regulatory/inventory lists including Canada; pharmaceutical, pharmaceutical, active_ingredient; animal_products; Europe; pharmaceutical; residue, and 1 more. Source: EPA CPDat.
Is Thimerosal used in cosmetics?
Yes, Thimerosal is also indexed as a cosmetic ingredient under the name Thimerosal (Thiomersal). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Thimerosal come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Thimerosal have different safety status in cosmetics vs industrial chemicals?
Thimerosal is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H317, H320, H341, H351, H360, H371, H372).
Is Thimerosal used outside industrial chemicals?
Thimerosal also appears in cosmetics, pharmaceutical databases.