What is the NOAEL for Ethyl 3-hydroxybutyrate?
Ethyl 3-hydroxybutyrate has 4 NOAEL studies in the database. The lowest reported value is 52008C87PV UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Ethyl 3-hydroxybutyrate
Also known as: Butyric acid, 3-hydroxy-, ethyl ester, Ethyl beta-hydroxybutyrate, Butanoic acid, 3-hydroxy-, ethyl ester, Ethyl (1)-3-hydroxybutyrate, EINECS 226-456-2 (+5 more)
CAS 5405-41-4
Ethyl 3-hydroxybutyrate (CAS 5405-41-4) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Ethyl 3-hydroxybutyrate
CAS Number
5405-41-4
DTXSID
DTXSID6025305
Molecular Formula
C6H12O3
InChI Key
OMSUIQOIVADKIM-UHFFFAOYSA-N
Monoisotopic Mass
132.078644
Synonyms
Butyric acid, 3-hydroxy-, ethyl esterEthyl beta-hydroxybutyrateButanoic acid, 3-hydroxy-, ethyl esterEthyl (1)-3-hydroxybutyrateEINECS 226-456-2EINECS 252-642-8FEMA No. 3428NSC 42916NSC 8115UNII-52008C87PV
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
FragranceFlavouring and nutrientSolvent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 52008C87PV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 52008C87PV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 52008C87PV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 52008C87PV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Ethyl 3-hydroxybutyrate?
Ethyl 3-hydroxybutyrate appears on 5 regulatory/inventory lists including SCIL (9/2019), IFRA Transparency, Europe, and 2 more. Source: EPA CPDat.
Is Ethyl 3-hydroxybutyrate used in cosmetics?
Yes, Ethyl 3-hydroxybutyrate is also indexed as a cosmetic ingredient under the name Ethyl 3-Hydroxybutyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ethyl 3-hydroxybutyrate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Ethyl 3-hydroxybutyrate used outside industrial chemicals?
Ethyl 3-hydroxybutyrate also appears in cosmetics, food safety databases.