What is the NOAEL for 2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene?
2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene has 4 NOAEL studies in the database. The lowest reported value is 1HAD3F3XM9 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene
Also known as: 1,3-Benzenediamine, 4,4'-[(4-methyl-1,3-phenylene)bis(azo)]bis[6-methyl-, dihydrochloride, 1,3-Benzenediamine, 4,4'-[(4-methyl-1,3-phenylene)bis(2,1-diazenediyl)]bis[6-methyl-, hydrochloride (1:2), C.I. Basic Brown 4, Astra Vesuvine B, Basic Brown 2K (+3 more)
CAS 5421-66-9
2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene (CAS 5421-66-9) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene
CAS Number
5421-66-9
DTXSID
DTXSID5063861
Molecular Formula
C21H24N8.2ClH
InChI Key
WLKAMFOFXYCYDK-UHFFFAOYSA-N
Monoisotopic Mass
460.165748
Synonyms
1,3-Benzenediamine, 4,4'-[(4-methyl-1,3-phenylene)bis(azo)]bis[6-methyl-, dihydrochloride1,3-Benzenediamine, 4,4'-[(4-methyl-1,3-phenylene)bis(2,1-diazenediyl)]bis[6-methyl-, hydrochloride (1:2)C.I. Basic Brown 4Astra Vesuvine BBasic Brown 2KBismark Brown REINECS 226-541-4NSC 7812
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1HAD3F3XM9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1HAD3F3XM9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1HAD3F3XM9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1HAD3F3XM9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Frequently Asked Questions
Is 2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene used in cosmetics?
Yes, 2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene is also indexed as a cosmetic ingredient under the name Basic Brown 4. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene come from?
Safety data is sourced from EPA ToxValDB, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene used outside industrial chemicals?
2,4-Bis(2,4-diamino-5-methyl-1-benzenazo)toluene also appears in cosmetics databases.