Basic Brown 4

INCI: BASIC BROWN 4

CAS Number
5421-66-9
Function
Hair colorant (bis-azo dye)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not an FDA-approved color additive; coal tar hair dye exemption may apply

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Bis-azo dye with two azo bonds that may release multiple aromatic amines upon reductive cleavage. Structural alert for mutagenicity with no genotoxicity, DART, or repeated-dose safety data available. Cannot be used compliantly without a complete safety dossier.

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Concern Level: High

Regulatory Flags

colorant

Frequently Asked Questions

Is Basic Brown 4 safe in cosmetics?

Bis-azo dye with two azo bonds that may release multiple aromatic amines upon reductive cleavage. Structural alert for mutagenicity with no genotoxicity, DART, or repeated-dose safety data available. Cannot be used compliantly without a complete safety dossier. The EU classifies Basic Brown 4 as "prohibited". Safety rating: POOR.

Is Basic Brown 4 allowed in the EU?

Basic Brown 4 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Basic Brown 4 do in cosmetics?

Basic Brown 4 functions as: Hair colorant (bis-azo dye). It is classified as a cosmetic ingredient in our database. CAS number: 5421-66-9.

What is the Margin of Safety for Basic Brown 4?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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