What is the NOAEL for 3,5,5-Trimethylhexanal?
3,5,5-Trimethylhexanal has 7 NOAEL studies in the database. The lowest reported value is U62H30BXPJ UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3,5,5-Trimethylhexanal
Also known as: 4-01-00-03362, BRN 1740882, tert-Butylisopentanal, EINECS 226-603-0, FEMA No. 3524 (+6 more)
CAS 5435-64-3
3,5,5-Trimethylhexanal (CAS 5435-64-3) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
3,5,5-Trimethylhexanal
CAS Number
5435-64-3
DTXSID
DTXSID6047107
Molecular Formula
C9H18O
InChI Key
WTPYRCJDOZVZON-UHFFFAOYSA-N
Monoisotopic Mass
142.135765
Synonyms
4-01-00-03362BRN 1740882tert-ButylisopentanalEINECS 226-603-0FEMA No. 3524Hexanal, 3,5,5-trimethl-IsononylaldehydeNSC 214823,5,5-TrimethylcapronaldehydeUNII-U62H30BXPJHexanal, 3,5,5-trimethyl-
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
9 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| U62H30BXPJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U62H30BXPJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U62H30BXPJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U62H30BXPJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3,5,5-trimethylhexanal | 226-603-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185108
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 3,5,5-Trimethylhexanal?
3,5,5-Trimethylhexanal appears on 4 regulatory/inventory lists including air; detected; emissions; Europe; Toys and children's products, IFRA Transparency, Europe, and 1 more. Source: EPA CPDat.
Is 3,5,5-Trimethylhexanal used in cosmetics?
Yes, 3,5,5-Trimethylhexanal is also indexed as a cosmetic ingredient under the name Trimethylhexanal. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3,5,5-Trimethylhexanal come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 3,5,5-Trimethylhexanal used outside industrial chemicals?
3,5,5-Trimethylhexanal also appears in cosmetics, pharmaceutical databases.