What is the NOAEL for Dibutyl sulfide?
Dibutyl sulfide has 9 NOAEL studies in the database. The lowest reported value is 3E3H471GA3 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Dibutyl sulfide
Also known as: 4-01-00-01559, BRN 1732829, n-Butyl-sulfide, Di-n-butylsulfide, EINECS 208-870-5 (+3 more)
CAS 544-40-1
Dibutyl sulfide (CAS 544-40-1) is a chemical substance. Key regulatory status: 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Dibutyl sulfide
CAS Number
544-40-1
DTXSID
DTXSID6022058
Molecular Formula
C8H18S
InChI Key
HTIRHQRTDBPHNZ-UHFFFAOYSA-N
Monoisotopic Mass
146.112922
Synonyms
4-01-00-01559BRN 1732829n-Butyl-sulfideDi-n-butylsulfideEINECS 208-870-5FEMA No. 22151,1'-Thiobis(butane)UNII-3E3H471GA3
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 3E3H471GA3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3E3H471GA3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3E3H471GA3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3E3H471GA3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 581 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 5400 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =2220 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 9 of 9 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3561568
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Dibutyl sulfide?
Dibutyl sulfide appears on 4 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, and 1 more. Source: EPA CPDat.
Is Dibutyl sulfide used in cosmetics?
Yes, Dibutyl sulfide is also indexed as a cosmetic ingredient under the name Dibutyl Sulphide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dibutyl sulfide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Dibutyl sulfide used outside industrial chemicals?
Dibutyl sulfide also appears in cosmetics, pharmaceutical, cannabis databases.