What is the NOAEL for C.I. Pigment Yellow 83?
C.I. Pigment Yellow 83 has 9 NOAEL studies in the database. The lowest reported value is 67HO7X7FV3 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
C.I. Pigment Yellow 83
Also known as: Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-, Disazo Yellow, Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-, Acetoacetanilide, 2,2''-[(3,3'-dichloro-4,4'-biphenylylene)bis(azo)]bis[4'-chloro-2',5'-dimethoxy-, 2,2'-[(3,3'-Dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutanamide] (+15 more)
CAS 5567-15-7
C.I. Pigment Yellow 83 (CAS 5567-15-7) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
9
SOURCE
Chemical inventory jurisdictions
Regulatory lists
8
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
C.I. Pigment Yellow 83
CAS Number
5567-15-7
Molecular Formula
C36H32Cl4N6O8
InChI Key
NKXPXRNUMARIMZ-UHFFFAOYSA-N
Monoisotopic Mass
816.103573
Synonyms
Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-Disazo YellowButanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-Acetoacetanilide, 2,2''-[(3,3'-dichloro-4,4'-biphenylylene)bis(azo)]bis[4'-chloro-2',5'-dimethoxy-2,2'-[(3,3'-Dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutanamide]2,2'-[(3,3'-Dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutanamideAquafine Yellow E 12C.I. 21108Chromofine Yellow 2700(L)Colanyl Yellow HRDFG 1842Graphtol Yellow RCL
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
46 records
DyePigmentDegradant/impurityProcessing aids not otherwise specified
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | European Commission | CosIng |
| Arts and crafts/Office supplies - body paint - tattoo ink; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; Europe | Danish Environmental Protection Agency | Danish EPA |
| Europe; plastic_additive | European Chemicals Agency | European Chemicals Agency (ECHA) |
| Europe | European Chemicals Agency | European Chemicals Agency (ECHA) |
| Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; Europe | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 67HO7X7FV3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >0.23 | mg/L | LC50 | Inhalation | - | NTP ICE acute inhalation |
| >4.25 | mg/L | LC50 | Inhalation | - | NTP ICE acute inhalation |
| =10 | mg/m3 | LEL | inhalation | Rat | ToxValDB EPA TSCA 8e |
| =30 | mg/m3 | LEL | inhalation | Rat | ToxValDB EPA TSCA 8e |
| =555 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
| =630 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB HPVIS |
| =702 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =1665 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutyramide] | 226-939-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Colorants
Frequently Asked Questions
What regulatory lists include C.I. Pigment Yellow 83?
C.I. Pigment Yellow 83 appears on 5 regulatory/inventory lists including Europe; Personal care, Arts and crafts/Office supplies - body paint - tattoo ink; Europe, Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe, and 2 more. Source: EPA CPDat.
Is C.I. Pigment Yellow 83 used in cosmetics?
Yes, C.I. Pigment Yellow 83 is also indexed as a cosmetic ingredient under the name CI 21108. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for C.I. Pigment Yellow 83 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is C.I. Pigment Yellow 83 used outside industrial chemicals?
C.I. Pigment Yellow 83 also appears in cosmetics databases.