NOAEL Data REACH Registered Cosmetic Ingredient

C.I. Pigment Yellow 83

Also known as: Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-, Disazo Yellow, Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-, Acetoacetanilide, 2,2''-[(3,3'-dichloro-4,4'-biphenylylene)bis(azo)]bis[4'-chloro-2',5'-dimethoxy-, 2,2'-[(3,3'-Dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutanamide] (+15 more)

CAS 5567-15-7

C.I. Pigment Yellow 83 (CAS 5567-15-7) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for CI 21108 →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields

Name

C.I. Pigment Yellow 83

CAS Number

5567-15-7

DTXSID

DTXSID1021453

Molecular Formula

C36H32Cl4N6O8

InChI Key

NKXPXRNUMARIMZ-UHFFFAOYSA-N

Monoisotopic Mass

816.103573

Synonyms

Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-Disazo YellowButanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-Acetoacetanilide, 2,2''-[(3,3'-dichloro-4,4'-biphenylylene)bis(azo)]bis[4'-chloro-2',5'-dimethoxy-2,2'-[(3,3'-Dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutanamide]2,2'-[(3,3'-Dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutanamideAquafine Yellow E 12C.I. 21108Chromofine Yellow 2700(L)Colanyl Yellow HRDFG 1842Graphtol Yellow RCL

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 46 records

DyePigmentDegradant/impurityProcessing aids not otherwise specified

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 8 records

List	Keyword	Source
Europe; Personal care	European Commission	CosIng
Arts and crafts/Office supplies - body paint - tattoo ink; Europe	Danish Environmental Protection Agency	Danish EPA
Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe	Danish Environmental Protection Agency	Danish EPA
Arts and crafts/Office supplies - body paint - tattoo ink; Europe	Danish Environmental Protection Agency	Danish EPA
Europe; plastic_additive	European Chemicals Agency	European Chemicals Agency (ECHA)
Europe	European Chemicals Agency	European Chemicals Agency (ECHA)
Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe	Danish Environmental Protection Agency	Danish EPA
Arts and crafts/Office supplies - body paint - tattoo ink; Europe	Danish Environmental Protection Agency	Danish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 12 of 12 studies

Value	Unit	Endpoint	Route	Species	Source
67HO7X7FV3	UNII	FDA UNII substance identifier	-	-	openFDA substances
67HO7X7FV3	UNII	FDA UNII substance identifier	-	-	openFDA substances
67HO7X7FV3	UNII	FDA UNII substance identifier	-	-	openFDA substances
67HO7X7FV3	UNII	FDA UNII substance identifier	-	-	openFDA substances
>0.23	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
>4.25	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
=10	mg/m3	LEL	inhalation	Rat	ToxValDB_EPA_TSCA_8e
=30	mg/m3	LEL	inhalation	Rat	ToxValDB_EPA_TSCA_8e
=555	mg/kg bw/day	NOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID
=630	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_HPVIS
=702	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=1665	mg/kg bw/day	NOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID

Showing 12 of 12 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutyramide]	226-939-8	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

restricted

Max

Frequently Asked Questions

What is the NOAEL for C.I. Pigment Yellow 83?

C.I. Pigment Yellow 83 has 12 NOAEL studies in the database. The lowest reported value is 67HO7X7FV3 UNII. Source: openFDA substances.

What regulatory lists include C.I. Pigment Yellow 83?

C.I. Pigment Yellow 83 appears on 5 regulatory/inventory lists including Europe; Personal care, Arts and crafts/Office supplies - body paint - tattoo ink; Europe, Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe, and 2 more. Source: EPA CPDat.

Is C.I. Pigment Yellow 83 used in cosmetics?

Yes, C.I. Pigment Yellow 83 is also indexed as a cosmetic ingredient under the name CI 21108. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for C.I. Pigment Yellow 83 come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is C.I. Pigment Yellow 83 used outside industrial chemicals?

C.I. Pigment Yellow 83 also appears in cosmetics databases.