CI 21108

CAS Number
5567-15-7
Function
Colorant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Not listed as FDA-certified color additive for cosmetics; not in 21 CFR Part 74 or 82

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CI 21108 is restricted in the EU to rinse-off cosmetics only but prohibited in the US as it is not FDA-approved for cosmetic use; moderate concern due to dichlorobenzidine-related contamination risk in the diarylide pigment class.

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Concern Level: Moderate

Regulatory Flags

azo-dye pigment diarylide rinse-off-only eu-annex-iv-restricted not-fda-approved dcb-concern eu_cosing_listed

Frequently Asked Questions

Is CI 21108 safe in cosmetics?

CI 21108 is restricted in the EU to rinse-off cosmetics only but prohibited in the US as it is not FDA-approved for cosmetic use; moderate concern due to dichlorobenzidine-related contamination risk in the diarylide pigment class. The EU classifies CI 21108 as "restricted". Safety rating: MODERATE.

Is CI 21108 allowed in the EU?

CI 21108 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 21108 do in cosmetics?

CI 21108 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 5567-15-7.

What is the Margin of Safety for CI 21108?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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