What is the NOAEL for Glycine?
Glycine has 7 NOAEL studies in the database. The lowest reported value is TE7660XO1C UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Glycine
Also known as: Amino-acetic acid, Amitone, EINECS 200-272-2, FEMA No. 3287, GLY (+15 more)
CAS 56-40-6
Glycine (CAS 56-40-6) is a chemical substance. Key regulatory status: REACH registered, 13 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
13
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Glycine
CAS Number
56-40-6
DTXSID
DTXSID9020667
Molecular Formula
C2H5NO2
InChI Key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
Monoisotopic Mass
75.032028
Synonyms
Amino-acetic acidAmitoneEINECS 200-272-2FEMA No. 3287GLYL-GlycineGlycine, non-medicalHampshire glycineSucre de gelatineAminoazijnzuurAminoacetic acid 1.5% in plastic containerGlycine 1.5% in plastic container
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
31 records
Anti-static agentSoftener and conditionerpH regulating agentFragranceFlavouring and nutrientHumectantProcessing aids not otherwise specifiedSolventAntioxidant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
13 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| animal_products | USDA | United States Department of Agriculture (USDA) |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Personal care; Southeast Asia | Asean | ASEAN Cosmetics |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| TE7660XO1C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TE7660XO1C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TE7660XO1C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TE7660XO1C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =7930 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 1600 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 10000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Glycine | 200-272-2 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
GLYCINE
ChEMBL Phase
4
Adverse Events
42
Bioactivity
8
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Glycine?
Glycine appears on 10 regulatory/inventory lists including active_ingredient; Australia, active_ingredient; animal_products; Europe; pharmaceutical; residue, children; Europe; Personal care, and 7 more. Source: EPA CPDat.
Is Glycine used in cosmetics?
Yes, Glycine is also indexed as a cosmetic ingredient under the name Glycine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Glycine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Glycine used outside industrial chemicals?
Glycine also appears in cosmetics, pharmaceutical, food safety, cannabis databases.