What is the NOAEL for 3-Methoxy-3-methylbutan-1-ol?
3-Methoxy-3-methylbutan-1-ol has 5 NOAEL studies in the database. The lowest reported value is 80 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3-Methoxy-3-methylbutan-1-ol
Also known as: 1-Butanol, 3-methoxy-3-methyl-, EINECS 260-252-4, 3-Methoxy-3-methyl-1-butanol, 3-Methyl-3-methoxybutanol, UNII-366754K2K1
CAS 56539-66-3
3-Methoxy-3-methylbutan-1-ol (CAS 56539-66-3) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
3-Methoxy-3-methylbutan-1-ol
CAS Number
56539-66-3
DTXSID
DTXSID8044389
Molecular Formula
C6H14O2
InChI Key
MFKRHJVUCZRDTF-UHFFFAOYSA-N
Monoisotopic Mass
118.09938
Synonyms
1-Butanol, 3-methoxy-3-methyl-EINECS 260-252-43-Methoxy-3-methyl-1-butanol3-Methyl-3-methoxybutanolUNII-366754K2K1
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
16 records
SolventFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| air; Cleaning products and household care; detected; emissions | Elsevier | CPCat |
| air; detected; emissions; Personal care | Elsevier | CPCat |
| air; Cleaning products and household care - air freshener; detected; emissions | Elsevier | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =80 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 366754K2K1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 366754K2K1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 366754K2K1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 366754K2K1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-methoxy-3-methylbutan-1-ol | 260-252-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3188023
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 3-Methoxy-3-methylbutan-1-ol?
3-Methoxy-3-methylbutan-1-ol appears on 5 regulatory/inventory lists including IFRA Transparency, air; Cleaning products and household care; detected; emissions, air; detected; emissions; Personal care, and 2 more. Source: EPA CPDat.
Is 3-Methoxy-3-methylbutan-1-ol used in cosmetics?
Yes, 3-Methoxy-3-methylbutan-1-ol is also indexed as a cosmetic ingredient under the name Methoxymethylbutanol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Methoxy-3-methylbutan-1-ol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-Methoxy-3-methylbutan-1-ol used outside industrial chemicals?
3-Methoxy-3-methylbutan-1-ol also appears in cosmetics, pharmaceutical databases.