NOAEL Data Cosmetic Ingredient

Sucrose

Also known as: alpha-D-Glucopyranoside, beta-D-fructofuranosyl, D(+)-Sucrose, alpha-D-Glucopyranoside, beta-D-fructofuranosyl-, .alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl, Amerfand (+15 more)

CAS 57-50-1

Sucrose (CAS 57-50-1) is a chemical substance. Key regulatory status: 44 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ILO ICSC, OSHA.

View cosmetic safety profile for Sucrose →

SOURCE NOAEL studies
NOAEL studies
37
SOURCE Chemical inventory jurisdictions
Regulatory lists
44
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 25 fields
Name
Sucrose
CAS Number
57-50-1
Molecular Formula
C12H22O11
InChI Key
CZMRCDWAGMRECN-UGDNZRGBSA-N
Monoisotopic Mass
342.116212
Synonyms
alpha-D-Glucopyranoside, beta-D-fructofuranosylD(+)-Sucrosealpha-D-Glucopyranoside, beta-D-fructofuranosyl-.alpha.-D-Glucopyranoside, .beta.-D-fructofuranosylAmerfandEINECS 200-334-9Fructofuranoside, alpha-D-glucopyranosyl, beta-Dbeta-D-Fructofuranosyl alpha-D-glucopyranosideGlucopyranoside, beta-D-fructofuranosyl, alpha-Dalpha-D-Glucopyranosyl beta-D-fructofuranoside(alpha-D-Glucosido)-beta-D-fructofuranosideNCI-C56597

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE WHO/JECFA 1 records
FieldValue
Short-term EffectsMay cause mechanical irritation.
Long-term EffectsThe substance may have effects on the teeth. This may result in dental caries. Repeated or prolonged contact with skin may cause dermatitis.
Routes of ExposureThe substance can be absorbed into the body by inhalation and by ingestion.

OSHA Exposure Limits

Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.

SOURCE OSHA / NIOSH / ACGIH occupational exposure limits 4 records
AgencyMetricValueppmmg/m3Skin
OSHATWA15 mg/m³ (total dust), 5 mg/m³ (respirable fraction)-15N
NIOSHTWA10 mg/m³ (total), 5 mg/m³ (resp)-10N
ACGIHTWA10 mg/m³ [1992]-10N
CAL/OSHATWA10 mg/m³ (total dust), 5 mg/m³ (respirable fraction)-10N

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records
HumectantSoftener and conditionerBinderFlavouring and nutrientFragranceProcessing aids not otherwise specified

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 44 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
pharmaceuticalUS International Trade CommissionCPCat
active_ingredient; Europe; PesticidesEuropean CommissionCPCat
active_ingredient; AustraliaAustralian Pesticides and Veterinary Medicines AuthorityCPCat
inert_ingredient; non_food_use; PesticidesEPACPCat
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - specialized bath products - bath saltsDanish Environmental Protection AgencyDanish EPA
animal_productsUSDAUnited States Department of Agriculture (USDA)
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
SCIL (9/2019)USEPASafer Chemical Ingredients List
Canada; pharmaceuticalDrugBankDrugBank
Canada; pharmaceuticalDrugBankDrugBank
Canada; pharmaceuticalDrugBankDrugBank
Cleaning products and household care - laundry and fabric treatment - laundry detergent; EuropeDanish EPADanish EPA
Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; EuropeDanish EPADanish EPA
fracking; waterNY Department of ConservationCPCat
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesCalifornia Department of Pesticide RegulationState of California
inert_ingredient; PesticidesEPACPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 37 of 37 studies
ValueUnitEndpointRouteSpeciesSource
C151H8M554UNIIFDA UNII substance identifier--openFDA substances
conceptidentifierFDA UNII substance identifier--openFDA substances
=2.970e+4mg/kg bwLD50oralRatNTP ICE acute oral
0unitlessModel Score--NTP ICE endocrine
1600mg/kg bw/dayNOAELoralratCOSMOS DB
7500mg/kg bw/dayNOAELoralratCOSMOS DB
9900mg/kg bw/dayNOAELoralrabbitCOSMOS DB
1.000e+4mg/kg bw/dayNOAELoralmouseCOSMOS DB
1.500e+4mg/kg bw/dayNOAELoralmouseCOSMOS DB
2.000e+4mg/kg bw/dayNOAELoralswineCOSMOS DB
2.070e+4mg/kg bw/dayNOAELoralrabbitCOSMOS DB
2.300e+4mg/kg bw/dayNOAELoralratCOSMOS DB
2.700e+4mg/kg bw/dayNOAELoralratCOSMOS DB
2.800e+4mg/kg bw/dayNOAELoralratCOSMOS DB
2.850e+4mg/kg bw/dayNOAELoralratCOSMOS DB
3.000e+4mg/kg bw/dayNOAELoralratCOSMOS DB
3.100e+4mg/kg bw/dayNOAELoralratCOSMOS DB
3.125e+4mg/kg bw/dayNOAELoralratCOSMOS DB
3.250e+4mg/kg bw/dayNOAELoralratCOSMOS DB
3.400e+4mg/kg bw/dayNOAELoralratCOSMOS DB
3.450e+4mg/kg bw/dayNOAELoralmonkeyCOSMOS DB
3.600e+4mg/kg bw/dayNOAELoralratCOSMOS DB
3.750e+4mg/kg bw/dayNOAELoralmonkeyCOSMOS DB
3.850e+4mg/kg bw/dayNOAELoralmonkeyCOSMOS DB
4.000e+4mg/kg bw/dayNOAELoralmonkeyCOSMOS DB
5.000e+4mg/kg bw/dayNOAELoralratCOSMOS DB
6.000e+4mg/kg bw/dayNOAELoralratCOSMOS DB
6.300e+4mg/kg bw/dayNOAELoralratCOSMOS DB
6.500e+4mg/kg bw/dayNOAELoralratCOSMOS DB
6.750e+4mg/kg bw/dayNOAELoralmouseCOSMOS DB
6.800e+4mg/kg bw/dayNOAELoralratCOSMOS DB
7.200e+4mg/kg bw/dayNOAELoralsyrian hamsterCOSMOS DB
7.300e+4mg/kg bw/dayNOAELoralratCOSMOS DB
8.100e+4mg/kg bw/dayNOAELoralhamsterCOSMOS DB
9.900e+4mg/kg bw/dayNOAELoralmouseCOSMOS DB
1.050e+5mg/kg bw/dayNOAELoralmouseCOSMOS DB
=6000ppmNOELoralRatToxValDB ECOTOX

Showing 37 of 37 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE ChEMBL / DailyMed SUCROSE
ChEMBL Phase
3
Adverse Events
366
Bioactivity
5
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA 1 records

1 food-safety record found.

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Sucrose?

Sucrose has 37 NOAEL studies in the database. The lowest reported value is C151H8M554 UNII. Source: openFDA substances.

What regulatory lists include Sucrose?

Sucrose appears on 16 regulatory/inventory lists including IFRA Transparency, pharmaceutical, active_ingredient; Europe; Pesticides, and 13 more. Source: EPA CPDat.

What are the occupational exposure limits for Sucrose?

Occupational exposure limits for Sucrose are set by OSHA, NIOSH, ACGIH. 4 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.

Is Sucrose used in cosmetics?

Yes, Sucrose is also indexed as a cosmetic ingredient under the name Sucrose. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Sucrose come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Sucrose used outside industrial chemicals?

Sucrose also appears in cosmetics, pharmaceutical, food safety, cannabis databases.