Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Sucrose. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 67500 mg/kg bw/day | oral | mouse | Short Term Toxicity | COSMOS_DB |
| NOAEL | 28500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 34500 mg/kg bw/day | oral | monkey | Short Term Toxicity | COSMOS_DB |
| NOAEL | 34500 mg/kg bw/day | oral | monkey | Short Term Toxicity | COSMOS_DB |
| NOAEL | 40000 mg/kg bw/day | oral | monkey | Short Term Toxicity | COSMOS_DB |
| NOAEL | 20000 mg/kg bw/day | oral | swine | Chronic | COSMOS_DB |
| NOAEL | 60000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 9900 mg/kg bw/day | oral | rabbit | Short Term Toxicity | COSMOS_DB |
| NOAEL | 105000 mg/kg bw/day | oral | mouse | Short Term Toxicity | COSMOS_DB |
| NOAEL | 27000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Microbial growth substrate — adequate preservative system mandatory in aqueous formulations; no other significant concerns
Regulatory Flags
Frequently Asked Questions
Is Sucrose safe in cosmetics?
Microbial growth substrate — adequate preservative system mandatory in aqueous formulations; no other significant concerns The EU classifies Sucrose as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Sucrose allowed in the EU?
Sucrose EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sucrose do in cosmetics?
Sucrose functions as: Humectant, skin conditioning agent, flavoring agent, bulking agent. It is classified as a cosmetic ingredient in our database. CAS number: 57-50-1.
What is the Margin of Safety for Sucrose?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sucrose?
The NOAEL (No Observed Adverse Effect Level) for Sucrose is 67500 mg/kg bw/day based on a Short Term Toxicity study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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