What is the NOAEL for 3-Hexanone?
3-Hexanone has 5 NOAEL studies in the database. The lowest reported value is P601A79G79 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3-Hexanone
Also known as: 4-01-00-03301, BRN 1738025, EINECS 209-645-4, FEMA No. 3290, Aethylpropylketon (+1 more)
CAS 589-38-8
3-Hexanone (CAS 589-38-8) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Ethyl Propyl Ketone (3-Hexanone) →
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
3-Hexanone
CAS Number
589-38-8
DTXSID
DTXSID2021608
Molecular Formula
C6H12O
InChI Key
PFCHFHIRKBAQGU-UHFFFAOYSA-N
Monoisotopic Mass
100.088815
Synonyms
4-01-00-03301BRN 1738025EINECS 209-645-4FEMA No. 3290AethylpropylketonUNII-P601A79G79
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| P601A79G79 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P601A79G79 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P601A79G79 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P601A79G79 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =40965.9 | mg/m3 | LEL | inhalation | Human | ToxValDB_DOE_Protective_Action_Criteria |
Showing 5 of 5 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3184187
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include 3-Hexanone?
3-Hexanone appears on 3 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe. Source: EPA CPDat.
Is 3-Hexanone used in cosmetics?
Yes, 3-Hexanone is also indexed as a cosmetic ingredient under the name Ethyl Propyl Ketone (3-Hexanone). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Hexanone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-Hexanone used outside industrial chemicals?
3-Hexanone also appears in cosmetics, pharmaceutical, food safety databases.