Ethyl Propyl Ketone (3-Hexanone)

INCI: ETHYL PROPYL KETONE

CAS Number
589-38-8
Function
Fragrance / Perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Not genotoxic; not phototoxic/photoallergenic; no PBT concerns; safety supported by read-across to 2-heptanone (CAS 110-43-0); standard volatile ketone handling precautions recommended.

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Concern Level: Low

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Ethyl Propyl Ketone (3-Hexanone) safe in cosmetics?

Not genotoxic; not phototoxic/photoallergenic; no PBT concerns; safety supported by read-across to 2-heptanone (CAS 110-43-0); standard volatile ketone handling precautions recommended. The EU classifies Ethyl Propyl Ketone (3-Hexanone) as "permitted". Safety rating: GOOD.

Is Ethyl Propyl Ketone (3-Hexanone) allowed in the EU?

Ethyl Propyl Ketone (3-Hexanone) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Propyl Ketone (3-Hexanone) do in cosmetics?

Ethyl Propyl Ketone (3-Hexanone) functions as: Fragrance / Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 589-38-8.

What is the Margin of Safety for Ethyl Propyl Ketone (3-Hexanone)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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