What is the NOAEL for 3-octanol?
3-octanol has 5 NOAEL studies in the database. The lowest reported value is 73DZ0U3U1E UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3-octanol
Also known as: (+/-)-3-Octanol, 1-Ethylhexanol, Amylethylcarbinol, Ethyl amyl carbinol, DL-3-Octanol (+2 more)
CAS 589-98-0
3-octanol (CAS 589-98-0) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
5
SOURCE
Chemical inventory jurisdictions
Regulatory lists
3
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
3-octanol
CAS Number
589-98-0
Molecular Formula
C8H18O
InChI Key
NMRPBPVERJPACX-UHFFFAOYSA-N
Monoisotopic Mass
130.135765
Synonyms
(+/-)-3-Octanol1-EthylhexanolAmylethylcarbinolEthyl amyl carbinolDL-3-OctanolEthylamylcarbinoln-Octan-3-ol
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 73DZ0U3U1E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 8100 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Octan-3-ol | 209-667-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
3-OCTANOL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3-octanol?
3-octanol appears on 3 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe. Source: EPA CPDat.
Is 3-octanol used in cosmetics?
Yes, 3-octanol is also indexed as a cosmetic ingredient under the name 3-Octanol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-octanol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-octanol used outside industrial chemicals?
3-octanol also appears in cosmetics, pharmaceutical, cannabis databases.