What is the NOAEL for Guanidine carbonate?
Guanidine carbonate has 5 NOAEL studies in the database. The lowest reported value is 3.31 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Guanidine carbonate
Also known as: Carbonic acid, compd. with guanidine (1:2), Bisguanidinium carbonate, EINECS 209-813-7, Guanidinium carbonate, NSC 2171 (+2 more)
CAS 593-85-1
Guanidine carbonate (CAS 593-85-1) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Guanidine carbonate is classified GHS Danger (H302, H315, H318, H319, H335, H412) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Guanidine carbonate
CAS Number
593-85-1
DTXSID
DTXSID0029189
Molecular Formula
2CH5N3.CH2O3
InChI Key
STIAPHVBRDNOAJ-UHFFFAOYSA-N
Monoisotopic Mass
180.097088
Synonyms
Carbonic acid, compd. with guanidine (1:2)Bisguanidinium carbonateEINECS 209-813-7Guanidinium carbonateNSC 2171Guanidine carbonate (2:1)UNII-V3394X3G2W
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
Softener and conditionerpH regulating agentHair waving or straightening
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =3.31 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| V3394X3G2W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V3394X3G2W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V3394X3G2W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V3394X3G2W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Diguanidinium carbonate | 209-813-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectants
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3187576
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
Is Guanidine carbonate used in cosmetics?
Yes, Guanidine carbonate is also indexed as a cosmetic ingredient under the name Guanadinium Carbonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Guanidine carbonate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Guanidine carbonate have different safety status in cosmetics vs industrial chemicals?
Guanidine carbonate is classified GHS Danger (H302, H315, H318, H319, H335, H412) in the chemicals database but is allowed in EU cosmetics.
Is Guanidine carbonate used outside industrial chemicals?
Guanidine carbonate also appears in cosmetics, pharmaceutical databases.