NOAEL Data Cosmetic Ingredient

4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1)

CAS 5985-28-4

4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1) (CAS 5985-28-4) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Synephrine HCl →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1)
CAS Number
5985-28-4
DTXSID
DTXSID70975251
Molecular Formula
C9H13NO2.ClH
InChI Key
COTCEGYSNTWJQV-UHFFFAOYSA-N
Monoisotopic Mass
203.071306

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
AntioxidantSoftener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
EN5D1IH09SUNIIFDA UNII substance identifier--openFDA substances
EN5D1IH09SUNIIFDA UNII substance identifier--openFDA substances
EN5D1IH09SUNIIFDA UNII substance identifier--openFDA substances
EN5D1IH09SUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1)?

4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1) has 4 NOAEL studies in the database. The lowest reported value is EN5D1IH09S UNII. Source: openFDA substances.

Is 4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1) used in cosmetics?

Yes, 4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1) is also indexed as a cosmetic ingredient under the name Synephrine HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1) used outside industrial chemicals?

4-[1-Hydroxy-2-(methylamino)ethyl]phenol--hydrogen chloride (1/1) also appears in cosmetics databases.