What is the NOAEL for P-Tolyl benzoate?
P-Tolyl benzoate has 8 NOAEL studies in the database. The lowest reported value is TRF6AI5R4X UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
P-Tolyl benzoate
Also known as: Benzoic acid, 4-methylphenyl ester, Benzoic acid, p-tolyl ester, 4-09-00-00306, BRN 1873141, p-Cresol benzoate (+6 more)
CAS 614-34-6
P-Tolyl benzoate (CAS 614-34-6) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
P-Tolyl benzoate
CAS Number
614-34-6
DTXSID
DTXSID6060632
Molecular Formula
C14H12O2
InChI Key
LLRZUDIHEZXFGV-UHFFFAOYSA-N
Monoisotopic Mass
212.08373
Synonyms
Benzoic acid, 4-methylphenyl esterBenzoic acid, p-tolyl ester4-09-00-00306BRN 1873141p-Cresol benzoatep-Cresyl benzoate4-Cresyl benzoateEINECS 210-380-14-Methylphenyl benzoateNSC 137593NSC 8788
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| TRF6AI5R4X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TRF6AI5R4X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TRF6AI5R4X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TRF6AI5R4X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =2644 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
BENZOIC ACID 4-METHYLPHENYL ESTER
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include P-Tolyl benzoate?
P-Tolyl benzoate appears on 2 regulatory/inventory lists including IFRA Transparency, consumer_product. Source: EPA CPDat.
Is P-Tolyl benzoate used in cosmetics?
Yes, P-Tolyl benzoate is also indexed as a cosmetic ingredient under the name p-Cresyl Benzoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for P-Tolyl benzoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is P-Tolyl benzoate used outside industrial chemicals?
P-Tolyl benzoate also appears in cosmetics, pharmaceutical databases.