Is p-Cresyl Benzoate safe in cosmetics?
p-Cresyl Benzoate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
p-Cresyl Benzoate
Also known as: Benzoic acid, 4-methylphenyl ester, Benzoic acid, p-tolyl ester, 4-09-00-00306, BRN 1873141, p-Cresol benzoate (+5 more)
INCI: P-CRESYL BENZOATE
p-Cresyl Benzoate (CAS 614-34-6) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 614-34-6 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(4-methylphenyl) benzoate
InChIKey
LLRZUDIHEZXFGV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA — not specifically restricted; general cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for p-Cresyl Benzoate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for p-Cresyl Benzoate.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Benzoic acid, 4-methylphenyl ester
Benzoic acid, p-tolyl ester
4-09-00-00306
BRN 1873141
p-Cresol benzoate
4-Cresyl benzoate
EINECS 210-380-1
4-Methylphenyl benzoate
NSC 137593
NSC 8788
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BENZOIC ACID 4-METHYLPHENYL ESTER
ChEMBL ID
CHEMBL2260449
Frequently Asked Questions
Is p-Cresyl Benzoate allowed in the EU?
p-Cresyl Benzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does p-Cresyl Benzoate do in cosmetics?
p-Cresyl Benzoate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 614-34-6.
Is p-Cresyl Benzoate used outside cosmetics?
p-Cresyl Benzoate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check p-Cresyl Benzoate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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