What is the NOAEL for Ethoxylated hydrogenated castor oil?
Ethoxylated hydrogenated castor oil has 58 NOAEL studies in the database. The lowest reported value is 0 unitless via Ocular in Rabbit. Source: NTP_ICE_eye_irritation.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ethoxylated hydrogenated castor oil
Also known as: HCO 40, HCO 50, Castor oil, hydrogenated, ethoxylated, Cremophor RH 40, Polyoxyethylene hydrogenated castor oil 60 (+13 more)
CAS 61788-85-0
Ethoxylated hydrogenated castor oil (CAS 61788-85-0) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for PEG-40 Hydrogenated Castor Oil →
SOURCE
noael studies public
NOAEL studies
58
SOURCE
chemical inventory jurisdictions
Regulatory lists
8
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
Ethoxylated hydrogenated castor oil
CAS Number
61788-85-0
DTXSID
DTXSID8044171
Synonyms
HCO 40HCO 50Castor oil, hydrogenated, ethoxylatedCremophor RH 40Polyoxyethylene hydrogenated castor oil 60EC No.: 500-147-5EC No.: 613-097-5EC No.: 918-326-5UNII-7YC686GQ8FUNII-02NG325BQGUNII-0ZNO9PJJ9JUNII-R07D3A9614
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Surfactant (surface active agent)EmulsifierSoftener and conditionerFragranceSolvent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Europe; Personal care - body hygiene - hand soap | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - body hygiene - body wash | Danish Environmental Protection Agency | Danish EPA |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 50 of 58 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| - | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| - | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| - | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| - | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 4 | unitless | EPA Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 4 | unitless | EPA Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 4 | unitless | EPA Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 4 | unitless | EPA Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 02NG325BQG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 02NG325BQG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 02NG325BQG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 02NG325BQG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0WZF1506N9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0WZF1506N9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0WZF1506N9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0WZF1506N9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0ZNO9PJJ9J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0ZNO9PJJ9J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0ZNO9PJJ9J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0ZNO9PJJ9J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43SW2U113W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43SW2U113W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43SW2U113W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43SW2U113W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7YC686GQ8F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7YC686GQ8F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7YC686GQ8F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7YC686GQ8F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| MH590ECD4O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| MH590ECD4O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| MH590ECD4O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| MH590ECD4O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R07D3A9614 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R07D3A9614 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R07D3A9614 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R07D3A9614 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WE09129TH5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WE09129TH5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WE09129TH5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WE09129TH5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Y825U5K7BE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Y825U5K7BE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Y825U5K7BE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Y825U5K7BE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.01 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| 0.01 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| 0.01 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| 0.01 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| >180 | s | Lag time | Ocular | - | NTP_ICE_eye_irritation |
| >180 | s | Lag time | Ocular | - | NTP_ICE_eye_irritation |
Showing 50 of 58 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Castor oil, hydrogenated, ethoxylated | 500-147-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
surfactant
Frequently Asked Questions
What regulatory lists include Ethoxylated hydrogenated castor oil?
Ethoxylated hydrogenated castor oil appears on 7 regulatory/inventory lists including Indirect additives food contact (10/2018), IFRA Transparency, inert_ingredient; non_food_use; Pesticides, and 4 more. Source: EPA CPDat.
Is Ethoxylated hydrogenated castor oil used in cosmetics?
Yes, Ethoxylated hydrogenated castor oil is also indexed as a cosmetic ingredient under the name PEG-40 Hydrogenated Castor Oil. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ethoxylated hydrogenated castor oil come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Ethoxylated hydrogenated castor oil used outside industrial chemicals?
Ethoxylated hydrogenated castor oil also appears in cosmetics databases.