Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for PEG-40 Hydrogenated Castor Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 5000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1250 mg/kg bw/day | oral | dog | oral | REACH |
Expert Verdict
CAS 61788-85-0. EU: Permitted, no restrictions. US: CIR-affirmed safe up to 100%; FDA no restriction. 1,4-dioxane impurity possible from ethoxylation -- controllable via purification.
Regulatory Flags
Frequently Asked Questions
Is PEG-40 Hydrogenated Castor Oil safe in cosmetics?
CAS 61788-85-0. EU: Permitted, no restrictions. US: CIR-affirmed safe up to 100%; FDA no restriction. 1,4-dioxane impurity possible from ethoxylation -- controllable via purification. The EU classifies PEG-40 Hydrogenated Castor Oil as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is PEG-40 Hydrogenated Castor Oil allowed in the EU?
PEG-40 Hydrogenated Castor Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-40 Hydrogenated Castor Oil do in cosmetics?
PEG-40 Hydrogenated Castor Oil functions as: Surfactant, solubilizer. It is classified as a Surfactant in our database. CAS number: 61788-85-0.
What is the Margin of Safety for PEG-40 Hydrogenated Castor Oil?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for PEG-40 Hydrogenated Castor Oil?
The NOAEL (No Observed Adverse Effect Level) for PEG-40 Hydrogenated Castor Oil is 5000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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