What is the NOAEL for 1,2,3-Propanetriyl triheptanoate?
1,2,3-Propanetriyl triheptanoate has 13 NOAEL studies in the database. The lowest reported value is 2P6O7CFW5K UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1,2,3-Propanetriyl triheptanoate
Also known as: Propane-1,2,3-triyl triheptanoate, Heptanoic acid, 1,2,3-propanetriyl ester, Heptanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester, Heptanoin, tri-, Dermofeel TC 7 (+12 more)
CAS 620-67-7
1,2,3-Propanetriyl triheptanoate (CAS 620-67-7) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
13
SOURCE
Chemical inventory jurisdictions
Regulatory lists
5
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
1,2,3-Propanetriyl triheptanoate
CAS Number
620-67-7
Molecular Formula
C24H44O6
InChI Key
PJHKBYALYHRYSK-UHFFFAOYSA-N
Monoisotopic Mass
428.313789
Synonyms
Propane-1,2,3-triyl triheptanoateHeptanoic acid, 1,2,3-propanetriyl esterHeptanoic acid, 1,1',1''-(1,2,3-propanetriyl) esterHeptanoin, tri-Dermofeel TC 7Glycerol triheptanoateGlyceryl triheptanoateLanol 37TTrienanthoinTriheptanoic glycerideTriheptanoinTrioenanthoin
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
8 records
Surfactant (surface active agent)Softener and conditionerViscosity modifierHumectantThickening agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 13 of 13 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 2P6O7CFW5K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =3.5 | g/kg/day | NOAEL | oral | rat | CIR Safety Assessment |
| =5 | % | NOAEL | oral | rat | CIR Safety Assessment |
| =10 | mg/kg bw/d | NOAEL | oral | rat | CIR Safety Assessment |
| =10 | g/kg | NOAEL | oral | rat | CIR Safety Assessment |
| =15 | % | NOAEL | oral | rat | CIR Safety Assessment |
| =3500 | mg/kg/d | NOAEL | oral | rat | CIR Safety Assessment |
| 3.5 | g/kg/day | oral toxicity | oral | rat | Regulatory source |
| 10 | g/kg | oral toxicity | oral | rat | Regulatory source |
| 15 | % | oral toxicity | oral | rat | Regulatory source |
| 5 | % | repeated dose toxicity | oral | rat | Regulatory source |
| 10 | mg/kg bw/d | repeated dose toxicity | oral | rat | Regulatory source |
| 3500 | mg/kg/d | repeated dose toxicity | oral | rat | Regulatory source |
Showing 13 of 13 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Propane-1,2,3-triyl trisheptanoate | 210-647-2 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
TRIHEPTANOIN
ChEMBL Phase
4
Adverse Events
15
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 1,2,3-Propanetriyl triheptanoate?
1,2,3-Propanetriyl triheptanoate appears on 3 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is 1,2,3-Propanetriyl triheptanoate used in cosmetics?
Yes, 1,2,3-Propanetriyl triheptanoate is also indexed as a cosmetic ingredient under the name Triheptanoin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,2,3-Propanetriyl triheptanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 1,2,3-Propanetriyl triheptanoate used outside industrial chemicals?
1,2,3-Propanetriyl triheptanoate also appears in cosmetics, pharmaceutical databases.