Is Triheptanoin safe in cosmetics?
Triheptanoin has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Triheptanoin
INCI: TRIHEPTANOIN
Triheptanoin (CAS 620-67-7) is a cosmetic cosmetic ingredient functioning as Emollient, skin conditioning agent, occlusive, viscosity controlling agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 620-67-7 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient, skin conditioning agent, occlusive, viscosity controlling agent
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2,3-di(heptanoyloxy)propyl heptanoate
InChIKey
PJHKBYALYHRYSK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA approved as pharmaceutical (Dojolvi/UX007) for LC-FAOD; COSMOS-approved; CIR Safe as used (2017/2018)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Triheptanoin.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Triheptanoin.
Regulatory Flags
PENETRATION_ENHANCER
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
TRIHEPTANOIN
ChEMBL ID
CHEMBL4297585
Max Phase
4
Adverse Event Associations
15
Frequently Asked Questions
Is Triheptanoin allowed in the EU?
Triheptanoin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Triheptanoin do in cosmetics?
Triheptanoin functions as: Emollient, skin conditioning agent, occlusive, viscosity controlling agent. It is classified as a cosmetic ingredient in our database. CAS number: 620-67-7.
Is Triheptanoin used outside cosmetics?
Triheptanoin also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Triheptanoin compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Is Triheptanoin in Your Products?
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