NOAEL Data Cosmetic Ingredient

1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2)

Also known as: EINECS 228-293-2, Fourrine 4G, o-Phenylenediamine, 4-nitro-, dihydrochloride, UNII-10T46XHE84

CAS 6219-77-8

1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2) (CAS 6219-77-8) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for 4-Nitro-O-Phenylenediamine HCl →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 10 fields
Name
1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2)
CAS Number
6219-77-8
DTXSID
DTXSID8064141
Molecular Formula
C6H7N3O2.2ClH
InChI Key
JMSFOGFLPAGXLG-UHFFFAOYSA-N
Monoisotopic Mass
225.007182
Synonyms
EINECS 228-293-2Fourrine 4Go-Phenylenediamine, 4-nitro-, dihydrochlorideUNII-10T46XHE84

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
Dye

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
10T46XHE84UNIIFDA UNII substance identifier--openFDA substances
10T46XHE84UNIIFDA UNII substance identifier--openFDA substances
10T46XHE84UNIIFDA UNII substance identifier--openFDA substances
10T46XHE84UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2)?

1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2) has 4 NOAEL studies in the database. The lowest reported value is 10T46XHE84 UNII. Source: openFDA substances.

Is 1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2) used in cosmetics?

Yes, 1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2) is also indexed as a cosmetic ingredient under the name 4-Nitro-O-Phenylenediamine HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2) used outside industrial chemicals?

1,2-Benzenediamine, 4-nitro-, hydrochloride (1:2) also appears in cosmetics databases.