Is 4-Nitro-O-Phenylenediamine HCl safe in cosmetics?
4-Nitro-O-Phenylenediamine HCl has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: restricted.
MODERATE
Cosmetic Ingredient
4-Nitro-O-Phenylenediamine HCl
Also known as: EINECS 228-293-2, Fourrine 4G, o-Phenylenediamine, 4-nitro-, dihydrochloride, UNII-10T46XHE84
INCI: 4-NITRO-O-PHENYLENEDIAMINE DIHYDROCHLORIDE
4-Nitro-O-Phenylenediamine HCl (CAS 6219-77-8) is a cosmetic cosmetic ingredient functioning as Oxidative hair dye (produces brown, red, blonde shades). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
Function
Oxidative hair dye (produces brown, red, blonde shades)
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Restricted; CIR-assessed with restrictions for use as hair dye
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 4-Nitro-O-Phenylenediamine HCl.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Editorial summary
Preliminary editorial summary for 4-Nitro-O-Phenylenediamine HCl — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
potential-allergen
Known Synonyms
EINECS 228-293-2
Fourrine 4G
o-Phenylenediamine, 4-nitro-, dihydrochloride
UNII-10T46XHE84
Chemical Function
Dye
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 4-Nitro-O-Phenylenediamine HCl allowed in the EU?
4-Nitro-O-Phenylenediamine HCl EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-Nitro-O-Phenylenediamine HCl do in cosmetics?
4-Nitro-O-Phenylenediamine HCl functions as: Oxidative hair dye (produces brown, red, blonde shades). It is classified as a cosmetic ingredient in our database. CAS number: 6219-77-8.
Compliance Tools
Check 4-Nitro-O-Phenylenediamine HCl compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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