What is the NOAEL for Sodium Gualenate?
Sodium Gualenate has 5 NOAEL studies in the database. The lowest reported value is 19WSH095WP UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Sodium Gualenate
Also known as: Azulen SN, Azupromin, 3,8-Dimethyl-5-(1-methylethyl)-1-azulenesulfonic acid sodium salt, EINECS 228-309-8, Sodium guaiazulene-3-sulfonate (+7 more)
CAS 6223-35-4
Sodium Gualenate (CAS 6223-35-4) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Sodium Gualenate
CAS Number
6223-35-4
DTXSID
DTXSID40211279
Molecular Formula
C15H18O3S.Na
InChI Key
GEYJUFBPCGDENK-UHFFFAOYSA-M
Synonyms
Azulen SNAzupromin3,8-Dimethyl-5-(1-methylethyl)-1-azulenesulfonic acid sodium saltEINECS 228-309-8Sodium guaiazulene-3-sulfonateSodium 7-isopropyl-1,4-dimethylazulene-3-sulfonateGuajazulen-3-sulfonsaeure, natriumsalzGualenate de sodiumGualenato sodidicoNatrii gualenasNatrium 7-isopropyl-1,4-dimethyl-3-azulensulfonatGualenato sodico
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Surfactant (surface active agent)
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 19WSH095WP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 19WSH095WP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 19WSH095WP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 19WSH095WP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =6380 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SODIUM GUALENATE
ChEMBL Phase
2
Adverse Events
16
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Sodium Gualenate?
Sodium Gualenate appears on 1 regulatory/inventory list including pharmaceutical. Source: EPA CPDat.
Is Sodium Gualenate used in cosmetics?
Yes, Sodium Gualenate is also indexed as a cosmetic ingredient under the name Guaiazulene Sulfonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium Gualenate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium Gualenate used outside industrial chemicals?
Sodium Gualenate also appears in cosmetics, pharmaceutical databases.